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. Author manuscript; available in PMC: 2020 Feb 1.
Published in final edited form as: Eur J Immunol. 2018 Dec 21;49(2):266–276. doi: 10.1002/eji.201847852

Figure 5: Increased hAb response to immunization in CB6F1 mice was dependent on memory B cells.

Figure 5:

CB6F1 mice (n = 4 per experiment) were depleted of B cells in between primary infection and secondary immunization using 500 μg anti-CD20 Ab given i.p., then allowed to reconstitute their naïve B cell population as outlined in Supplementary Figure 5. Day 21 post A/PR8 HA immunization A/PR8 HAI titer in panel (A) and endpoint titer ± SD (Log10) in panel (B). (*p<0.05, **p<0.01, One-way ANOVA). Data show results from one of two experiments with similar results (n = 4 animals per experiment).