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. Author manuscript; available in PMC: 2020 Feb 26.
Published in final edited form as: ACS Nano. 2019 Feb 8;13(2):2398–2409. doi: 10.1021/acsnano.8b09266

Figure 1. Mechanisms of membrane ion channel gating.

Figure 1.

(a) Voltage-gated ion channel changes its conformation in response to an increase of the transmembrane bias. (b) Ligand-gated channel opens or closes its transmembrane pore in response to ligand binding. (c) Mechanosensitive channel opens when the membrane tension exceeds a threshold value. (d) The electromechanical gating by an insertable peptide gate investigated in this work.