Primary items		Other items
Methods
Study design	E.g. Parallel group RCT, paired‐eye RCT, cluster RCT, cross‐over RCT, or other design.	Exclusions after randomisation Losses to follow up How missing data were handled e.g. available case analysis, imputation methods Reported power calculation (Y/N), including sample size and power Unusual study design/issues (as required)
Unit of randomisation/unit of analysis	e.g. One eye included in study, two eyes included in study, both eyes received same treatment, or two eyes included in study, eyes received different treatments.
Participants
Country		Setting Equivalence of baseline characteristics
Total number of participants
Number (%) of men and women
Average age and age range
Inclusion criteria
Exclusion criteria
Interventions
Intervention (n = ) Comparator (n = )	· Number of people randomised to each group · Intervention name
Outcomes
Primary and secondary outcomes as defined in study reports	Details of outcomes Length of follow up and intervals at which outcomes assessed	Planned/actual length of follow up
Notes
Date conducted	Specify dates of recruitment of participants	Trial registration details Full study name: (if applicable) Author's name and contact details (email, mailing address) Were trial investigators contacted?
Sources of funding
Declaration of interest