Kara Junior 2011.

Methods	Study design: RCT Study grouping: parallel group, with paired‐eye comparison (i.e., one eye received a blue‐light filtering IOL and the fellow eye received a non‐blue‐light filtering IOL) Exclusions after randomisation: participants with incomplete follow‐up were not included in the analyses. Losses to follow‐up: during the five‐year study period, five participants were lost to follow‐up; therefore, 25 participants were considered in the analyses How missing data were handled: not reported Reported power size calculation? no
Participants	Baseline characteristics Blue‐light filtering IOL group Number of participants: number of people (number of eyes): 30 (30), with 25 (25) completed Sex (number of women/number of men): 10/15 Age (mean ± SD): 59.9 ± 7.0 years Non‐blue‐light filtering IOL group Number of participants: number of people (number of eyes): 30 (30), with 25 (25) completed Sex (number of women/number of men): 10/15 Age (mean ± SD): 59.9 ± 7.0 years Inclusion criteria: people with visually significant bilateral cataract and no history of colour vision deficiency were eligible for inclusion in the study. Exclusion criteria: ocular disease such as corneal opacity or irregularity, dry eye, amblyopia, anisometropia, glaucoma, retinal abnormalities; surgical complications; IOL tilt; previous or current use of medications known to cause colour‐vision deficiencies; incomplete follow‐up Comparison of study groups at baseline: paired‐eye trial, however participants who had surgical complications were excluded, and no details were provided about whether there were exclusions due to intraoperative complications.
Interventions	Intervention characteristics Blue‐light filtering IOL Type of IOL: Acrysof Natural SN60AT (Alcon) Non‐blue‐light filtering IOL Type of IOL: Acrysof SA60AT (Alcon)
Outcomes	The primary outcome measures were contrast sensitivity, colour vision and macular findings at five years after surgery.
Identification	Sponsorship source: Funding sources: no funding sources listed Declaration of interest: "No author has a financial or proprietary interest in any material or method mentioned." Country: Brazil Setting: Ophthalmology Department, University of Sao Paulo, Sao Paulo, Brazil Comments: Date study conducted: not reported Trial registration number: not reported Contacting study investigators: study authors contacted not contacted; no additional information used for review Corresponding author's name: Marcony R. Santhiago, MD Institution: Cole Eye Institute, Cleveland Clinic Email: marconysanthiago@hotmail.com Address: Cole Eye Institute Cleveland Clinic 1700 East 13th Street Apartment 15W, Cleveland, Ohio 44114, USA
Notes	None
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Judgement comment: not reported how list was generated. Study is described as “randomised” but with no further details
Allocation concealment (selection bias)	Unclear risk	Judgement comment: not reported how allocation administered. Study is described as “randomised” but with no further details
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Judgement comment: described as “double‐masked” with no information on who was masked
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Judgement comment: described as “double‐masked” with no information on who was masked
Incomplete outcome data (attrition bias) All outcomes	Low risk	Judgement comment: missing data less than 20% (i.e., more than 80% follow‐up), equal follow‐up in both groups (as paired‐eye study) and no obvious reason why loss to follow‐up should be related to outcome
Selective reporting (reporting bias)	Unclear risk	Judgement comment: no access to protocol or trials registry entry
Other bias	Low risk	Judgement comment: no other source of bias