Verma 2006

Methods	2‐arm active‐controlled double‐dummy randomised trial.
Participants	Between 2005 and 2006, 200 parturients were randomised in a hospital setting in India. The population comprised women of unspecified parity, unspecified whether singleton or multiple pregnancy, at low risk for PPH, who delivered by vaginal delivery. Exclusion criteria were not specified.
Interventions	400 mcg of misoprostol administered sublingually (n = 100) versus 200 mcg of ergometrine administered intramuscularly (n = 100).
Outcomes	The study recorded the following outcomes: PPH at 500, additional uterotonics, manual removal of placenta, blood loss (mL), change in Hb level, third‐stage duration (min), nausea, fever, shivering.
Notes	Contact with study authors for additional information: yes. Additional data from authors: no.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Randomisation sequence generation was not reported.
Allocation concealment (selection bias)	Unclear risk	Allocation concealment was not reported.
Blinding of participants and personnel (performance bias) All outcomes	Low risk	The study was "double‐blind": active treatments and placebo treatments were "identical‐looking."
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Assessors were blinded to treatment allocations.
Objective assessment of blood loss	Low risk	Investigators evaluated blood loss "accurately with a specially designed calibrated blood collection drape (BRASS‐V drape)."
Incomplete outcome data (attrition bias) All outcomes	Unclear risk	The study authors did not mention any incomplete outcome data.
Selective reporting (reporting bias)	Unclear risk	The protocol of the study was unavailable for verification.
Intention to treat analysis	Unclear risk	It was unclear from the study report whether all those who were enrolled and randomly allocated to treatment were included in the analysis, in the groups to which they were randomised.
Funding source	Unclear risk	Source(s) of funding for the study were unclear.