Moodie 1976

Methods	2‐arm active‐controlled randomised trial.
Participants	Between dates unspecified, 148 parturients were randomised in a hospital setting in the UK. The population comprised women of unspecified parity, a singleton pregnancy, at high risk for PPH, who delivered by vaginal delivery. Exclusion criteria were not specified.
Interventions	500 mcg of ergometrine administered by an intravenous bolus (n = 78) versus 5 IU of oxytocin administered by an intravenous bolus (n = 70).
Outcomes	The study recorded the following outcomes: PPH at 500, blood loss (mL), nausea.
Notes	Contact with study authors for additional information: no. Additional data from authors: no.
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Randomisation sequence generation was not reported.
Allocation concealment (selection bias)	Unclear risk	Allocation concealment was not reported.
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Blinding (of study participants and caregivers) was not reported.
Blinding of outcome assessment (detection bias) All outcomes	Unclear risk	Assessor blinding was not reported.
Objective assessment of blood loss	Low risk	Investigators evaluated blood loss by collection with the placenta bowl and soiled linen and swabs. "The principles of the haemoglobin extraction‐dilution technique employed have been discussed by Roe, Gardiner and Dudley (1962) and Thornton and colleagues (1963)."
Incomplete outcome data (attrition bias) All outcomes	High risk	There were 148 study participants but blood loss data were available in only 80 cases.
Selective reporting (reporting bias)	Unclear risk	The protocol of the study was unavailable for verification.
Intention to treat analysis	Low risk	All those who were enrolled and randomly allocated to treatment were included in the analysis, in the groups to which they were randomised.
Funding source	Unclear risk	Source(s) of funding for the study were not reported.