Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2019 May 1;5(5):eaaw1616. doi: 10.1126/sciadv.aaw1616

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2019 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

This is an open-access article distributed under the terms of the Creative Commons Attribution license, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Fig. 3 — (A) After principal components analysis, we generated 10 maps, each representing the median orientation of the particles within each specific subset. A bottom view of two of these maps is shown, highlighting the movement of PIH1D1 within the structure. The mobile element, comprising PIH1D1 and the DII domain, is enclosed within a red line. (B) Side view of one of the maps generated after multibody refinement. Observed motions are proximal to regions of the RUVBL1-RUVBL2 ring, suggesting that conformational changes in the DII domain could be coupled to changes in the ring. A red line is used to highlight the proximity between the mobile elements and the RUVBL1-RUVBL2 ring.