Comparison 4. Mineral trioxide aggregate (MTA) pulpotomy versus ferric sulphate (FS) pulpotomy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Clinical failure	4		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
1.1 6 months	4	190	Risk Ratio (M‐H, Fixed, 95% CI)	0.08 [0.00, 1.31]
1.2 12 months	3	130	Risk Ratio (M‐H, Fixed, 95% CI)	0.2 [0.01, 3.97]
1.3 24 months	3	130	Risk Ratio (M‐H, Fixed, 95% CI)	0.52 [0.20, 1.39]
2 Radiological failure	4		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 6 months	4	190	Risk Ratio (M‐H, Fixed, 95% CI)	0.06 [0.01, 0.40]
2.2 12 months	3	130	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.15, 3.44]
2.3 24 months	3	130	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.25, 1.36]
3 Overall failure	4		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 6 months	4	190	Risk Ratio (M‐H, Fixed, 95% CI)	0.06 [0.01, 0.40]
3.2 12 months	3	130	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.15, 3.44]
3.3 24 months	3	130	Risk Ratio (M‐H, Fixed, 95% CI)	0.78 [0.32, 1.89]
4 Pain	3		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
4.1 6 months	3	160	Risk Ratio (M‐H, Fixed, 95% CI)	0.2 [0.01, 4.00]
4.2 12 months	2	100	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
5 Soft tissue pathology	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
5.1 6 months	2	110	Risk Ratio (M‐H, Fixed, 95% CI)	0.2 [0.01, 4.00]
6 Pathologic mobility	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
6.1 6 months	2	110	Risk Ratio (M‐H, Fixed, 95% CI)	0.08 [0.00, 1.31]
7 Pathologic radiolucency	3		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
7.1 6 months	3	160	Risk Ratio (M‐H, Fixed, 95% CI)	0.03 [0.00, 0.48]
7.2 12 months	2	100	Risk Ratio (M‐H, Fixed, 95% CI)	0.33 [0.01, 7.81]
7.3 24 months	2	100	Risk Ratio (M‐H, Fixed, 95% CI)	0.2 [0.01, 3.97]
8 Pathological root resorption	4		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
8.1 6 months	4	190	Risk Ratio (M‐H, Fixed, 95% CI)	0.07 [0.01, 0.53]
8.2 12 months	3	130	Risk Ratio (M‐H, Fixed, 95% CI)	0.2 [0.01, 3.97]
8.3 24 months	3	130	Risk Ratio (M‐H, Fixed, 95% CI)	0.56 [0.12, 2.51]
9 Pulp canal obliteration	3		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
9.1 6 months	3	140	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
9.2 12 months	2	80	Risk Ratio (M‐H, Fixed, 95% CI)	3.0 [0.13, 70.30]
9.3 24 months	2	80	Risk Ratio (M‐H, Fixed, 95% CI)	1.57 [0.47, 5.27]