Comparison 8. Calcium hydroxide pulpotomy versus formocresol pulpotomy.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Clinical failure	6		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
1.1 6 months	6	332	Risk Ratio (M‐H, Fixed, 95% CI)	1.98 [1.17, 3.37]
1.2 12 months	6	332	Risk Ratio (M‐H, Fixed, 95% CI)	1.87 [1.22, 2.89]
1.3 24 months	3	150	Risk Ratio (M‐H, Fixed, 95% CI)	2.18 [0.78, 6.11]
2 Radiological failure	6		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
2.1 6 months	4	154	Risk Ratio (M‐H, Fixed, 95% CI)	15.48 [3.86, 62.06]
2.2 12 months	6	332	Risk Ratio (M‐H, Fixed, 95% CI)	1.86 [1.42, 2.44]
2.3 24 months	3	150	Risk Ratio (M‐H, Fixed, 95% CI)	3.63 [1.73, 7.61]
3 Overall failure	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
3.1 12 months	2	120	Risk Ratio (M‐H, Fixed, 95% CI)	2.41 [0.80, 7.21]
3.2 24 months	2	120	Risk Ratio (M‐H, Fixed, 95% CI)	2.93 [1.35, 6.34]
4 Pain	4		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
4.1 6 months	4	276	Risk Ratio (M‐H, Fixed, 95% CI)	3.18 [0.35, 29.08]
4.2 12 months	4	276	Risk Ratio (M‐H, Fixed, 95% CI)	6.30 [1.15, 34.40]
5 Soft tissue pathology	5		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
5.1 6 months	5	306	Risk Ratio (M‐H, Fixed, 95% CI)	5.14 [0.63, 42.25]
5.2 12 months	5	306	Risk Ratio (M‐H, Fixed, 95% CI)	6.77 [1.23, 37.10]
5.3 24 months	2	124	Risk Ratio (M‐H, Fixed, 95% CI)	2.64 [0.51, 13.55]
6 Pathological mobility	4		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
6.1 6 months	4	238	Risk Ratio (M‐H, Fixed, 95% CI)	1.21 [0.18, 8.19]
6.2 12 months	4	238	Risk Ratio (M‐H, Fixed, 95% CI)	1.14 [0.40, 3.31]
6.3 24 months	2	124	Risk Ratio (M‐H, Fixed, 95% CI)	9.0 [0.53, 153.79]
7 Pathological radiolucency	5		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
7.1 6 months	3	128	Risk Ratio (M‐H, Fixed, 95% CI)	3.78 [0.64, 22.17]
7.2 12 months	5	306	Risk Ratio (M‐H, Fixed, 95% CI)	1.90 [0.67, 5.40]
7.3 24 months	2	124	Risk Ratio (M‐H, Fixed, 95% CI)	3.24 [0.79, 13.28]
8 Pathological root resorption	6		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
8.1 6 months	4	154	Risk Ratio (M‐H, Fixed, 95% CI)	11.87 [2.33, 60.40]
8.2 12 months	6	332	Risk Ratio (M‐H, Fixed, 95% CI)	6.25 [2.04, 19.14]
8.3 24 months	3	150	Risk Ratio (M‐H, Fixed, 95% CI)	4.59 [1.33, 15.81]
9 Pulp canal obliteration	3		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
9.1 6 months	2	56	Risk Ratio (M‐H, Fixed, 95% CI)	4.0 [0.47, 33.75]
9.2 12 months	3	140	Risk Ratio (M‐H, Fixed, 95% CI)	2.68 [0.91, 7.95]
10 Dentin bridge formation	2		Risk Ratio (M‐H, Fixed, 95% CI)	Subtotals only
10.1 6 months	2	60	Risk Ratio (M‐H, Fixed, 95% CI)	13.0 [1.81, 93.60]
10.2 12 months	2	60	Risk Ratio (M‐H, Fixed, 95% CI)	14.0 [1.95, 100.26]