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. 2018 May 31;2018(5):CD003220. doi: 10.1002/14651858.CD003220.pub3

Ansari 2010.

Methods RCT, split‐mouth
Teeth randomly assigned
Conducted in the Paedodontic Department at Shahid Beheshti University, Dental School, Iran. Operator was an investigator
Participants 17 children, 40 teeth, age range 4 to 9 years
Interventions Group 1:Pulpotomy (formocresol); n = 20 (1 visit)
  • Rubber dam

  • Caries removal prior to pulpal access not mentioned

  • Pulp access not mentioned

  • Pulpotomy amputation with excavator

  • For haemostasis, moistened cotton pellet with saline

  • No irrigation

  • Cotton wool pellet soaked with FC placed on pulp stumps for 5 minutes after pulpotomy, followed by IRM dressings before being restored with amalgam or stainless‐steel crowns


Group 2:Pulpotomy (MTA); n = 20 (2 visits)
  • Rubber dam

  • Caries removal prior to pulpal access not mentioned

  • Pulp access not mentioned

  • Pulpotomy amputation with excavator

  • For haemostasis, moistened cotton pellet with saline

  • No irrigation

  • Cotton wool pellet soaked with FC placed on pulp stumps for 5 minutes after pulpotomy, followed by IRM dressings before being restored with amalgam or stainless‐steel crowns

  • MTA applied after pulpotomy, then temporarily filled using an IRM, until the second visit for placement of ZOE base. dressings before being restored with stainless‐steel crowns

Outcomes Signs of failure (internal resorption, radiographic signs of pathosis (periapical radiolucency), report of pain, presence of gingival swelling and sinus tract): evaluation at 24 months (at tooth level)
Fistula, furcal radiolucency, periapical radiolucency, internal resorption, external resorption, periodontal ligament widening, pulp canal obliteration: evaluation at 6, 12 and 24 months (at tooth level)
Notes Source of funding: not reported
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information to make a clear judgement
Allocation concealment (selection bias) Unclear risk Insufficient information to make a clear judgement
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Insufficient information to make a clear judgement
Blinding of clinical outcomes assessment Unclear risk Insufficient information to make a clear judgement
Blinding of radiological outcomes assessment Unclear risk Insufficient information to make a clear judgement
Incomplete outcome data (attrition bias) 
 All outcomes High risk Proportion of missing outcomes > 10% of children randomly assigned
Selective reporting (reporting bias) Unclear risk Insufficient information to make a clear judgement