Chandra 2014.

Methods	RCT, parallel‐arm Teeth randomly assigned Conducted in India. Operator not mentioned.
Participants	52 children, 60 teeth, 3.8 to 7.6 years
Interventions	Group 1:Pulpectomy (ozonated oil‐ZO); n = 30 (1 visit) Rubber dam Caries removal prior to pulpal access Pulp access Pulpotomy amputation not mentioned Instrumentation with barbed broaches and K‐files Irrigation with 2.5 % sodium hypochlorite and normal saline The root canals were filled 1 mm short of the apex with a mixture of ZO powder (0.2 g, arsenic free) and ozonated sesame oil using Lentulo spirals, before being restored with stainless steel crowns Group 2:Pulpectomy (ZOE); n = 30 (1 visit) Rubber dam Caries removal prior to pulpal access Pulp access Pulpotomy amputation not mentioned Instrumentation with barbed broaches and K‐files Irrigation with 2.5 % sodium hypochlorite and normal saline The root canals were filled 1 mm short of the apex with ZOE using Lentulo spirals, before being restored with stainless steel crowns
Outcomes	Clinical success (absence of pain, tenderness to percussion, absence or decrease in mobility and sinus opening), radiographic success (signs of resolution in the radiolucency, no new signs of post‐operative radiolucency and no signs of internal or external pathological root resorption), radiographic failure (increase in postoperative inter‐radicular radiolucency or development of new postoperative radiolucency): evaluation at 12 months
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Insufficient information to make a clear judgement
Allocation concealment (selection bias)	Unclear risk	Insufficient information to make a clear judgement
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Insufficient information to make a clear judgement
Blinding of clinical outcomes assessment	Low risk	Quote: "The teeth were evaluated for success or failure based on clinical and radiographic criteria by a blinded investigator"
Blinding of radiological outcomes assessment	Low risk	Quote: "The teeth were evaluated for success or failure based on clinical and radiographic criteria by a blinded investigator"
Incomplete outcome data (attrition bias) All outcomes	Low risk	No missing data
Selective reporting (reporting bias)	Unclear risk	Insufficient information to make a clear judgement