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. 2018 May 31;2018(5):CD003220. doi: 10.1002/14651858.CD003220.pub3

Durmus 2014.

Methods RCT, parallel‐arm
Teeth randomly assigned
Conducted in the University of Marmara, Department of Paediatric Dentistry, in Istanbul. Operator was one paediatric dentist.
Participants 58 children, 120 teeth, age range 5 to 9 years
Interventions Group 1:Pulpotomy (diode laser); n = 40 (1 visit)
  • Rubber dam

  • Caries removal prior to pulpal access not mentioned

  • Pulp access not mentioned

  • Pulpotomy amputation with slow speed followed by excavator

  • For haemostasis, dry cotton pellet

  • Irrigation not mentioned

  • A DL beam at a wavelength of 810 nm was transmitted. The DL fibre tip was kept 1–2mm from touching the tissue. The pulp at canal orifices was exposed with parameters of a frequency of 30 Hz and energy of 50 mJ, with a power of 1.5 W for 10 sec with air‐cooling operation mode without water. Followed by ZOE followed by glass ionomer cement before being restored with stainless‐steel crown


Group 2:Pulpotomy (formocresol); n = 40 (1 visit)
  • Rubber dam

  • Caries removal prior to pulpal access not mentioned

  • Pulp access not mentioned

  • Pulpotomy amputation with slow speed followed by excavator

  • For haemostasis, dry cotton pellet

  • Irrigation not mentioned

  • cotton pellet placed directly over the radicular pulp stumps and left for 5 min for fixation, followed by ZOE followed by glass ionomer cement before being restored with stainless‐steel crown


Group 3:Pulpotomy (ferric sulphate); n = 40 (1 visit)
  • Rubber dam

  • Caries removal prior to pulpal access not mentioned

  • Pulp access not mentioned

  • Pulpotomy amputation with slow speed followed by excavator

  • For haemostasis, dry cotton pellet

  • Irrigation not mentioned

  • FS applied by wiping the cotton tip on the pulp stumps for 15 sec. The pulp cavity was washed with saline to remove any blood clot particles, followed by ZOE followed by glass ionomer cement before being restored with stainless‐steel crown

Outcomes Clinical failure (spontaneous pain, percussion/palpation, abscess, swelling, fistula, or pathologic mobility), radiological failure (periapical radiolucency, widened periodontal ligament space (PDL), pathologic internal/external root resorption, or pathological changes of the alveolar bone in the furcation): evaluation at 1, 3, 6, 9, and 12 months
Notes  
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Insufficient information to make a clear judgement
Allocation concealment (selection bias) Unclear risk Insufficient information to make a clear judgement
Blinding of participants and personnel (performance bias) 
 All outcomes Unclear risk Insufficient information to make a clear judgement
Blinding of clinical outcomes assessment Low risk Quote: "The outcome assessment and data analysis were blinded "
Blinding of radiological outcomes assessment Unclear risk Quote: "The outcome assessment and data analysis were blinded " BUT "Two blinded observers evaluated a set of radiographs separately"
Incomplete outcome data (attrition bias) 
 All outcomes Low risk No missing data
Selective reporting (reporting bias) Unclear risk Insufficient information to make a clear judgement