Khorakian 2014.

Methods	RCT, split‐mouth Teeth randomly assigned Conducted in the paediatric department of Mashhad Dental School, Iran. Operator was a postgraduate student of paediatric dentistry, who was supervised by two academic staff
Participants	51 children, 102 teeth, age range 4 to 6 years
Interventions	Group 1:Pulpotomy (CEM); n = 51 (1 visit) Rubber dam Caries removal prior to pulpal access Pulp access with a high speed bur Pulpotomy amputation with slow speed bur For haemostasis, cotton pellets wet by sterile saline Irrigation not mentioned a 2 mm layer of CEM cement (BioniqueDent, Tehran, Iran) was applied directly over the radicular pulp. CEM was prepared using a 3 to 1 powder to liquid ratio, before being restored with stainless steel crown Group 2:Pulpotomy (ES/ZOE); n = 51 (1 visit) Rubber dam Caries removal prior to pulpal access Pulp access with a high speed bur Pulpotomy amputation with slow speed bur For haemostasis, cotton pellets wet by sterile saline Irrigation not mentioned ES ball‐shaped electrode was immediately used for tissue coagulation. The unit was set at 55 W, 3.69 MHz, 600 ohm, and COAG mode. The electrode was placed 1 to 2 mm above the pulp orifices and then electrical arc allowed to bridge for 1 s. This procedure was repeated up to three times on each pulpal orifice with 5 to 10 s cool‐down intervals, until a dark brown appearance was observed in the tissues. After copious irrigation, zinc oxide eugenol was placed directly on the radicular pulp stump, before being restored with stainless steel crown
Outcomes	Clinical success (lack of pain, mobility, swelling, sinus tract, tenderness to percussion and bone swelling), radiographic success (PDL and periapical regions with normal width and trabeculation minimal internal resorption), pulp canal obliteration: evaluation at 6, 12 and 24 months
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computerised random‐number
Allocation concealment (selection bias)	Unclear risk	Insufficient information to make a clear judgement
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Quote: "...both the patients and outcome assessors were blinded to the type of treatment"
Blinding of clinical outcomes assessment	Low risk	Quote: "...both the patients and outcome assessors were blinded to the type of treatment"
Blinding of radiological outcomes assessment	Low risk	Quote: "...both the patients and outcome assessors were blinded to the type of treatment"
Incomplete outcome data (attrition bias) All outcomes	High risk	Proportion of missing outcomes > 10% children randomly assigned
Selective reporting (reporting bias)	Unclear risk	Insufficient information to make a clear judgement