Markovic 2005.

Methods	RCT, parallel‐arm Children randomly assigned Conducted in the Clinic of Preventive and Pediatric Dentistry, School of Dentistry, University of Belgrade, Serbia and Montenegro. Operators were 3 paedodontists with a minimum of 5 years' clinical experience
Participants	104 children, 104 teeth, mean age 6.4 years, standard deviation age 1.1 years, age range 4 to 9 years
Interventions	Group 1:Pulpotomy (formocresol); n = 33 (1 visit) Cotton rolls Caries removal prior to pulpal access Pulp access with slow‐speed bur Pulpotomy amputation with high‐speed bur For haemostasis, dry cotton pellet Irrigation with saline Cotton wool pellet soaked with FC placed on pulp stumps for 5 minutes after pulpotomy. After removal of the FC‐soaked cotton pledget, the pulp chamber was rinsed with water using an air‐water syringe. The pulp chamber was dried with a sterile cotton pledget, followed by CH before being restored with glass‐ionomer cement as a liner and amalgam Group 2:Pulpotomy (calcium hydroxide); n = 34 (1 visit) Cotton rolls Caries removal prior to pulpal access Pulp access with slow‐speed bur Pulpotomy amputation with high‐speed bur For haemostasis, dry cotton pellet Irrigation with saline CH applied after pulpotomy, before being restored with glass‐ionomer cement as a liner and amalgam Group 3:Pulpotomy (ferric sulphate)n = 37 (1 visit) Cotton rolls Caries removal prior to pulpal access Pulp access with slow‐speed bur Pulpotomy amputation with high‐speed bur For haemostasis, dry cotton pellet Irrigation with saline FS (15.5%) applied to pulp stumps for 15 seconds, before being restored with glass‐ionomer cement as a liner and amalgam
Outcomes	Radiographic success (pathological changes of the alveolar bone in the apical or furcation (or both) area, visible periapical or inter‐radicular radiolucency, integrity of lamina dura, pathological internal resorption, external root resorption), spontaneous pain, abnormal mobility, tenderness to percussion, changes in the integrity of lamina dura, pathological internal resorption, external root resorption, dentine bridge formation, abscess or fistula, apical and furcal destruction: reporting at 3, 6, 12 and 18 months (at tooth level)
Notes	Source of funding: not reported
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Unclear risk	Insufficient information to make a clear judgement
Allocation concealment (selection bias)	Unclear risk	Insufficient information to make a clear judgement
Blinding of participants and personnel (performance bias) All outcomes	Unclear risk	Insufficient information to make a clear judgement
Blinding of clinical outcomes assessment	Unclear risk	Insufficient information to make a clear judgement
Blinding of radiological outcomes assessment	Unclear risk	Insufficient information to make a clear judgement
Incomplete outcome data (attrition bias) All outcomes	Low risk	No missing data
Selective reporting (reporting bias)	Unclear risk	Insufficient information to make a clear judgement