1. Antifibrinolytic agent vs control: menstrual blood loss.
Study | Comparison | Outcome | Intervention group | Control group | Finding (e.g. P value for difference between groups, as reported in primary study) | ||||
Intervention | n | Result (mean (SD)) | Intervention | n | Result (mean (SD)) | ||||
Jaisamrarn 2006 | TXA vs progestogens or NSAIDs | PBAC score | TXA 3 g daily | 56 | 204.4 (SD 255.7) | Norethisterone 10 mg daily (luteal phase) | 56 | 298.7 (SD 141.3) | P < 0.0001 |
Mefenamic acid 1.5 mg daily | 56 | 278.3 (SD 164.2) | P < 0.001 | ||||||
Preston 1995 | TXA vs luteal phase MPA | Mean loss by alkaline haematin method (end score) | TXA 4 g daily | 25 | 97 (SD 89) | Norethisterone (21 participants) 5 mg taken twice daily on days 19 to 26 of cycle. | 21 | 208 (SD 135) | P = 0.001 |