Study	Reason for exclusion
Andersch 1988	Cross‐over trial which did not report data from the first phase of the study.
Chamberlain 1991	Treatment group received ethamsylate.
Drosdal 1993	Participants included women with IUD in situ.
Harrison 1976	Treatment group received ethamsylate.
Kasonde 1975	Participants had intrauterine coil devices in situ.
Kouides 2009	Participants had a proven coagulopathy.
Moghtadaei 2012	Author was contacted for further information about their study, to judge whether it should be included/excluded. No reply was received.
Muse 2010	There was no control group.
Najam 2010	Compared women taking tranexamic acid to those taking a combination of tranexamic acid and mefenamic acid.
NCT01190150	Dose‐finding RCT of tranexamic acid in girls aged 12 to 16 years.
NCT01428713	Data not provided for the end of the first phase of the cross‐over study.
NiIsson 1965	Treatment group received ethamsylate.
Nilsson 1967	Cross‐over trial which did not report data from the first phase of the study.
Petersen 1983	Treatment was given for only 1 month. Criterion specified in our protocol was that we would include only studies using at least 2 months of treatment.
Tabatabaei 2013	Author was contacted for further information about their study, to judge whether it should be included/excluded. No reply was received.
Vermylen 1968	Cross‐over trial which did not report data from the first phase of the study.
Westrom 1970	Participants had intrauterine coil devices in situ.
Ylikorkala 1983	Participants had intrauterine coil devices in situ.