Date	Event	Description
17 January 2018	New citation required and conclusions have changed	Paracetamol has now been compared to placebo/no intervention and to indomethacin. Paracetamol appears more effective in closing a PDA than placebo/no intervention and has a similar effectiveness as ibuprofen or indomethacin with fewer side effects. Only one small study has reported on long‐term follow‐up.
17 January 2018	New search has been performed	The literature was searched in November 2017. Six new published trials and 16 new ongoing trials were identified.