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. 2018 Apr 3;2018(4):CD008133. doi: 10.1002/14651858.CD008133.pub2
No of studies Design Risk of bias Inconsistency Indirectness Imprecision Other Certainty
(overall score)
Outcome 1: Mortality of children ≤ 1 year in past year
1 Cluster RCT Serious (‐1)
Downgraded by 1 for serious risk of bias. Baseline participant characteristics are not reported.
No serious risk No serious risk Serious (‐1)
Downgraded by 1 for serious imprecision. The study reported Treatment of the Treated (ToT) estimates. Actual numbers for numerator and denominator not provided.
No serious risk Lowa, b
Downgraded by 2 because of serious RoB and Imprecision
Outcome 2: Child diarrhoea
1 Cluster RCT Serious (‐1)
Downgraded by 1 for serious risk of bias. Baseline participant characteristics are not reported.
No serious risk No serious risk Serious (‐1)
Downgraded by 1 for serious imprecision. The study reported Treatment of the Treated (ToT) estimates. Actual numbers for numerator and denominator not provided.
No serious risk Lowa, b
Downgraded by 2 because of serious RoB and Imprecision
Outcome 3: Child immunisation
2 Cluster RCT
Controlled Before‐After
Bloom 2006:Serious (‐1)
Downgraded by 1 for serious risk of bias. Baseline participant characteristics are not reported.
Cristia 2015: Serious (‐1)
Downgraded by 1 for serious risk of bias. The study is at a high risk of Other bias because the estimates of the effects correspond with a strengthened model of the intervention compared to the initial model.
No serious risk No serious risk Bloom 2006: No serious risk
(95% CI ‐10.0%; 25.2%) calculating width: 10.0%+25.2% = the width = 35.2% = not imprecise
Cristia 2015: No serious risk
Measles
(95% CI ‐9.4%; 102.4% ) calculating width: 9.4%+102.4%= the width = 111.8% = not imprecise
DPT
(95% CI ‐46.3%; 43.5%) calculating width: 46.3%+43.5% = the width = 89.8% = not imprecise
Polio
(95% CI ‐54.8% to 39.6%) calculating width: 54.8%+39.6% = the width = 94.4%= not imprecise
No serious risk Moderatec
Downgraded by 1 because of serious RoB