Khan (pers comm)

Trial name or title	TILT ‐ Time‐Lapse Imaging Trial
Methods	Multi‐centre randomised controlled trial
Participants	Participants undergoing IVF/ICSI treatment and: the woman is between 18‐42 years of age; receiving the first, second or third IVF/ICSI treatment cycle; those participants having at least 3 2PN embryos (showing 2 pro‐nuclei, which is a sign of normal fertilisation) on day of fertilisation check.
Interventions	Intervention 1: incubation and assessment of embryos using TLI systems (morphokinetic parameters + undisturbed culture + morphological assessment) Intervention 2: incubation of embryos in undisturbed culture and standard embryo assessment (undisturbed culture + morphological assessment) Control: standard care (morphological assessment alone)
Outcomes	Primary outcome: live birth rate. Secondary outcomes: clinical pregnancy rate, elective single embryo transfer rate, multiple birth rate, miscarriage of clinical pregnancy rate, stillbirth rate and major congenital abnormality rate.
Starting date	February 2018
Contact information	Professor Khalid Khan k.s.khan@qmul.ac.uk
Notes	CPMS ID 37510. Undergoing ISRCTN registration