Morino 2006.

Methods	Parallel randomised controlled clinical trial Randomisation ratio: superiority design
Participants	91 elective patients with cholelithiasis and common bile duct stones diagnosed at MRCP; mean age 59.5 years; male 38.4%; normal value of total bilirubin: 72.5%; normal value of gamma GT: 92%; normal value of AST: 80.15%; normal value of amylase: 26%; common bile duct diameter ⋝10 mm: 62.6% Inclusion criteria: people with gallbladder and main bile duct stones Exclusion criteria: acute cholangitis, necrotizing pancreatitis, age < 18 years, ASA status IV and V Diagnostic criteria: gallbladder and main bile duct stones were detected by transabdominal ultrasound and MRCP
Interventions	Number of study centres: one Treatment before study: not reported Type of interventions: 46 participants treated in a single step with videolaparoscopic cholecystectomy, intraoperative cholangiography, and endoscopic sphincterotomy during the surgical procedure with the rendezvous technique, and 45 treated with preoperative ERCP and endoscopic sphincterotomy using a traditional method of bile duct cannulation.
Outcomes	Morbidity, clinical pancreatitis, hyperamylasaemia, failure rate, mean hospital stay (days)
Notes	Run‐in period: from May 2001 to August 2005 Study terminated before regular end (for benefit or because of adverse events): no Follow‐up: 19 to 20 months Funding sources: no information reported Declaration of interest: no information reported Country: Italy
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Computer‐generated random numbers
Allocation concealment (selection bias)	Low risk	Sealed opaque envelopes
Blinding of participants and personnel (performance bias) All outcomes	High risk	Participants and personnel were not blinded
Blinding of outcome assessment (detection bias) All outcomes	High risk	Not clearly stated whether the outcome assessors were blinded to the treatments or not.
Incomplete outcome data (attrition bias) All outcomes	Low risk	None
Selective reporting (reporting bias)	Unclear risk	The study protocol was not available.
Other bias	High risk	The learning curve was not reported.
for‐profit bias	Unclear risk	Information about sponsorship or trial support not reported