Famularo 1987.

Methods	A naturalistic observational study, where the effectiveness of drug treatment (methylphenidate) were tested by a drug treatment during a grading period and no drug treatment for the next grading period
Participants	Number of patients screened: not stated Number of participants included: 13 Number of participants followed up: 10 Number of withdrawals: 3 Diagnosis of ADHD: DSM‐III diagnosis of ADD (subtype: inattentive) Age: mean: 9.4, range 7‐12 years old IQ: above 90 Sex: 4 males, 6 females Methylphenidate‐naïve: not stated Ethnicity: not stated Country: USA Comorbidity: not stated, but see exclusion criteria Comedication: not stated Sociodemographics: not stated Inclusion criteria ADD disorder according to DSM III Exclusion criteria IQ < 90 Anxiety or panic disorder Seizure disorder Major affective disorder Thought disorder Post‐traumatic stress syndrome, or medical or neurological disease No other DSM III diagnosis
Interventions	Methylphenidate type: not stated Methylphenidate dosage: 0.4 to 1.2 mg/kg/day Administration schedule: twice daily Duration of intervention: not stated Treatment compliance: not stated
Outcomes	Non‐serious adverse events: 1 child reported decreased appetite without weight loss Another child's sleep onset was 15‐20 minutes later than usual after initiation of pharmacological treatment There were minimal and clinically insignificant increases in pulse
Notes	Sample calculation: not stated Any withdrawals due to adverse events: no Ethics approval: not stated Funding/vested interest/authors' affiliations: not stated Key conclusions of the study authors: the results of this study provide tentative support for 2 conclusions: ADD without hyperactivity appears to be a potentially stimulant‐treatable condition, even though hyperactivity is specifically excluded from its symptomatology; and school grades in children with ADD without hyperactivity may be influenced by the use of stimulants Comments from the study authors: the fact that significant results were obtained with such a small sample reflects the consistency with which the effects of the medication were exhibited across participants. However, it cannot be argued that these 10 participants adequately represent all ADD without hyperactivity children. In addition, the results may have been affected by factors such as teacher bias, student motivation, and parental encouragement Supplemental information requested through personal email correspondence with the authors in August 2013 and January 2014. No reply