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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Findling 1996.

Methods A patient report of an 11‐year old girl who experienced transient side effects after receiving MPH
Participants Diagnosis of ADHD: DSM‐III‐R (subtype: combined)
Age: 11 years old
IQ: > 70
Sex: female
Ethnicity: not stated
Country: USA
Comorbidity: major depression (single episode, marked severity)
Comedication: sertraline 25 mg, twice daily
Sociodemographics: not stated
Interventions Methylphenidate dosage: 5 mg twice daily
Duration of intervention: the patient was still taking methylphenidate at the follow‐up at 3 months. Adverse effects occurred in the initiation of the treatment
Treatment compliance: not stated
Outcomes Non‐serious adverse events:
Mild and transient anorexia, transient weight loss 2 kg observed at the initiation of methylphenidate therapy
Notes Ethics approval: not stated
Funding/vested interests/authors' affiliations: not stated
Key conclusions of study authors: these cases support previous suggestions that adjunctive treatment with psychostimulants might be a safe and effective intervention for children treated with fluoxetine or sertraline who have persistent ADHD symptoms and suggest that such combined treatment might be suitable for adults as well
Supplemental information: email sent twice to author in order to get data on BP and HR. No reply