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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Irmak 2014.

Methods A patient report of phobias and visual hallucinations during methylphenidate treatment
Participants Diagnosis of ADHD: DSM‐IV (subtype: combined)
Age: 9 years old
IQ: WİSC‐R: performance IQ: 78, verbal IQ: 87
Sex: male
Ethnicity: not stated
Country: Turkey
Comorbidity: Moebius syndrome
Comedication: none
Sociodemographics: not stated
Interventions Methylphenidate type: osmotic release oral system (OROS)
Methylphenidate dosage: gradually titrated up to 1 mg/kg
Administration schedule: not stated
Duration of treatment: not stated
Treatment compliance: not stated
Outcomes Serious adverse events:
Methylphenidate prescribed at initial ADHD diagnosis, then withdrawn following the onset of phobias and visual hallucinations as well as lack of improvement in attention problems
Notes Key conclusions of the study authors: dramatic occurrence of adverse effects in our patients suggests that there is an increased vulnerability to adverse effects of methylphenidate in patients with syndromes when compared to other ADHD patients
Supplemental information regarding ADHD diagnosis, IQ and comedication received through personal email correspondence with the authors in June 2016 (Irmak 2016 [pers comm])