Karabekiroglu 2008.

Methods	A retrospective cohort of methylphenidate use for 6 months
Participants	Number of participants screened: not stated Number of participants included: 90 Diagnosis of ADHD: DSM‐IV diagnosis (subtype: not stated) Age: mean: 9.0, range: 5‐16 years old) IQ: above 70 Sex: 59 males, 14 females Methylphenidate‐naïve: 100% Ethnicity: not stated Country: Turkey Comorbidity: conduct disorder (16.7%); tics (23.3%); Tourette syndrome (10.5%); obsessive compulsive disorder (16.3%); pervasive developmental disorder (8.1%); learning disorder (26.7%); depression (9.2%) Comedication: none Sociodemographics: not stated Inclusion criteria: In a clinical sample In a period of 6 months, all methylphenidate‐naïve patients with attention deficit hyperactivity disorder, whose parents accepted to participate in the study with an informed consent, were included Exclusion criteria: Mental retardation
Interventions	Methylphenidate type: immediate release Methylphenidate dosage: 10‐30 mg/day Mean methylphenidate dosage: 17.6 (SD 4.95) mg/day Administration schedule: 2‐3 times/day Duration of intervention: 6 months Treatment compliance: not stated
Outcomes	Non‐serious adverse events: Parents completed the Barkley Stimulant Side Effects Rating Scale (BSSERS) at baseline and on the 3rd, 7th, and 15th days of the medication
Notes	Sample calculation: not stated Ethics approval: not stated Funding/vested interest: "This research had a naturalistic design. Therefore, a limited financial support, which was supplied by the authors, was needed." Key conclusions of the study authors: authors found significant decrease in appetite, and they suppose that some of the Barkley SES may represent both ADHD symptoms and methylphenidate adverse events Exclusion of methylphenidate non‐responders/children who have previously experienced adverse events on methylphenidate: all participants were methylphenidate‐naïve Supplemental information regarding the IQ of the participants received through personal email correspondence with the authors in June 2016 (Karabekiroglu 2016 [pers comm])