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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Langevin 2012.

Methods A controlled before‐after study of methylphenidate use for ADHD
Participants Number of participants screened: not stated
Number of participants included: 10
Number of participants included as cases: 5 and controls: 5
Number of participants followed up: 10
Number of withdrawals: 0
Diagnosis of ADHD: DSM‐IV TM (subtype: combined (80%); inattentive (20%))
Age: mean 8.13 years (range 7‐9)
IQ: normal
Sex: 8 males, 2 females
Methylphenidate‐naïve: not stated
Ethnicity: white (90%), African‐Canadian (10%)
Country: Canada
Comorbidity: 20% ODD, 10% seasonal affective disorder
Comedication: not stated
Sociodemographics: not stated
Interventions Methylphenidate type: immediate‐release or moderate‐release
Methylphenidate dosage: not stated
Administration schedule: not stated
Duration of intervention: 6 months
Treatment compliance: not stated
Outcomes Non‐serious adverse events:
Sleep quality and numbers of hours of sleep
Notes Sample calculation: not stated
Ethics approval: not stated
Funding/vested interests/authors' affiliations: this study was supported by a grant from the University of Alberta (Killam Research Fund)
Key conclusions of the study authors: the principal results support the study's hypothesis and show a significant baseline difference (P = 0.008) between the nocturnal movements of the ADHD children and those of the control children
Exclusion of methylphenidate non‐responders/children who have previously experienced adverse events on methylphenidate: no