Skip to main content
. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Munk 2015.

Methods A patient report of cardiac arrest following myocardial infarction during methylphenidate treatment
Participants Diagnosis of ADHD: ICD‐10
Age: 11 years old
IQ: unknown
Sex: male
Ethnicity: not stated
Country: Denmark
Comorbidity: Tourette syndrome
Comedication: none
Sociodemographics: not stated
Interventions Methylphenidate type and dosage: 54 mg/day
Administration schedule: not stated
Duration of treatment: approximately 2 years
Treatment compliance: yes
Outcomes Serious adverse events:
Cardiac arrest following exercise without any prior complaints about chest discomfort or shortness of breath. A week before the event, he had a short episode of tachycardia. The examination showed that the myocardial infarction was of an older date (more than weeks) due to thinning of the myocardium and an adversely remodeled left ventricle. A pacemaker was inserted and methylphenidate treatment was discontinued
Notes Key conclusions of the study authors: the present case demonstrates that myocardial infarction can happen due to methylphenidate exposure in a cardiac healthy child, without any other cardiovascular risk factors
 Comments from the study authors: the boy has been very thoroughly examined and the only thing that stands out is the methylphenidate treatment
Funding/vested interest/authors affiliations: the authors declare that there is no conflict of interests regarding the publication of this paper
Supplemental information regarding IQ and comedication received through personal email correspondence with the authors in April 2016 (Munk 2016 [pers comm]). Not possible to retrieve information regarding ADHD subtype