Munk 2015.
Methods | A patient report of cardiac arrest following myocardial infarction during methylphenidate treatment | |
Participants | Diagnosis of ADHD: ICD‐10 Age: 11 years old IQ: unknown Sex: male Ethnicity: not stated Country: Denmark Comorbidity: Tourette syndrome Comedication: none Sociodemographics: not stated |
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Interventions | Methylphenidate type and dosage: 54 mg/day Administration schedule: not stated Duration of treatment: approximately 2 years Treatment compliance: yes |
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Outcomes |
Serious adverse events: Cardiac arrest following exercise without any prior complaints about chest discomfort or shortness of breath. A week before the event, he had a short episode of tachycardia. The examination showed that the myocardial infarction was of an older date (more than weeks) due to thinning of the myocardium and an adversely remodeled left ventricle. A pacemaker was inserted and methylphenidate treatment was discontinued |
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Notes |
Key conclusions of the study authors: the present case demonstrates that myocardial infarction can happen due to methylphenidate exposure in a cardiac healthy child, without any other cardiovascular risk factors
Comments from the study authors: the boy has been very thoroughly examined and the only thing that stands out is the methylphenidate treatment Funding/vested interest/authors affiliations: the authors declare that there is no conflict of interests regarding the publication of this paper Supplemental information regarding IQ and comedication received through personal email correspondence with the authors in April 2016 (Munk 2016 [pers comm]). Not possible to retrieve information regarding ADHD subtype |