Niederhofer 2009.

Methods	A patient report of dosage reduction of methylphenidate treatment by addition of atomoxetine. Adverse effects of methylphenidate are reported
Participants	Diagnosis of ADHD: DSM‐IV (subtype: combined) Age: 11 years old IQ: 97 Sex: male Ethnicity: not stated Country: Italy Comorbidity: not stated Comedication: not stated Sociodemographics: not stated
Interventions	Methylphenidate type: not stated Methylphenidate dosage: 20 mg/day Administration schedule: not stated Duration of intervention: 2 months Treatment compliance: not stated
Outcomes	Non‐serious adverse events: Methylphenidate 20 mg/day: depressed mood and appetite loss Dosage‐reduction to 10 mg/day: improved the depressed mood
Notes	Key conclusions of study authors: the reported case mainly shows that the combination between atomoxetine and methylphenidate helped reducing the dose of methylphenidate and thus, probably the side effects while showing beneficial clinical effects Funding/vested interests/authors' affiliations: not stated Supplemental information regarding ADHD type received through personal email correspondence with author in July 2013 (Niederhofer 2013 [pers comm])