Central nervous system
Study	Symptom	Adverse events/total number of participants
Affect lability
Sahin 2014	Moodiness	10/30
Wigal 2013	Affect lability	12/44
Aggression
Barrickman 1995	Anger	1/15
Berek 2011	Aggressive reaction	13/762
Davari‐Ashtiani 2010	Aggression	1/16
Dittmann 2014	Aggression	0/195
Döpfner 2011a, OBSEER	Aggression	31/777
Döpfner 2011b	Aggression	2/113
Haertling 2015	Aggression	3/239
Kemner 2005 (FOCUS)	Aggression	10/850
Kordon 2011	Aggression	10/541
Lee 2014	Aggression	7/100
Mayes 1994	Aggression	1/69
Na 2013	Anger	6/103
Remschmidt 2005	Aggression	1/105
Wilens 2005	Hostility	8/407
Anorexia
Arabgol 2015	Anorexia	8/15
Arnold 2004	Anorexia	16/76
Arnold 2010	Anorexia	6/150
Berek 2011	Anorexia	35/762
Cortese 2015	Anorexia	9/1426
Döpfner 2011a, OBSEER	Anorexia	9/777
Döpfner 2011b	Anorexia	0/113
Gerwe 2009	Anorexia	20/263
Greenhill 1983	Anorexia	5/7
Haertling 2015	Anorexia	11/239
Khajehpiri 2014	Anorexia	45/71
Kordon 2011	Anorexia	23/541
Kratochvil 2002	Anorexia	6/25
Lee 2007	Anorexia	29/110
Na 2013	Anorexia	66/103
Song 2012	Anorexia	104/116
Wang 2007	Anorexia	42/166
Warshaw 2010	Anorexia	9/260
Weiss 2007	Anorexia	16/79
Wilens 2006	Anorexia	22/220
Yildiz 2011	Anorexia	9/11
Zelnik 2015	Anorexia	36/128
Çetin 2015	Anorexia	12/61
Anxiety
Abbasi 2011	Anxiety	9/20
Akhondzadeh 2003	Anxiety	3/10
Akhondzadeh 2004	Anxiety	3/20
Amiri 2008	Anxiety, nervousness	4/27
Barrickman 1995	Anxiety	1/15
Blader 2010	Anxiety or nervousness	12/65
Davari‐Ashtiani 2010	Phobia & anxiety	2/16
Efron 1997	Anxiousness	76/123
El‐Fiky 2014	Anxious	2/31
Gau 2006	Anxious	10/32
Ghanizadeh 2012	Anxiety	1/12
Green 2011	Anxiousness	4/14
Hammerness 2009	Anxiety	2/57
Hazell 2003	Anxious	6/10
Jafarinia 2012	Anxiety	5/20
Maia 2008	Anxious	12/31
Mohammadi 2004	Anxiety	0/11
Mohammadi 2010	Anxiety	9/19
Na 2013	Anxiety	9/103
Song 2012	Anxiety	12/116
Wilens 2005	Anxiety	9/407
Zelnik 2015	Anxiety	21/128
Fingernail biting
Blader 2010	Bites fingernails	9/65
Efron 1997	Biting fingernails	56/123
El‐Fiky 2014	Bites fingers	0/31
Gau 2006	Biting fingernails	8/32
Green 2011	Biting fingernails	3/14
Hazell 2003	Biting fingernails	2/10
Maia 2008	Bites fingernails	3/31
Sahin 2014	Nail biting	3/30
Shang 2015	Nail biting	1/66
Daydreams
Efron 1997	Daydreams	77/123
Gau 2006	Daydreams	10/32
Green 2011	Daydreams	3/14
Sahin 2014	Daydreams	7/30
Difficulty falling asleep
Akhondzadeh 2003	Difficulty falling asleep	4/10
Akhondzadeh 2004	Difficulty falling asleep	6/20
Altin 2013	Insomnia	5/71
Amiri 2008	Difficulty falling asleep	8/30
Ardic 2014	Insomnia	19/101
Arnold 2004	Insomnia	16/76
Arnold 2010	Insomnia	9/171
Atzori 2009	Insomnia	3/129
Barrickman 1995	Insomnia	1/15
Berek 2011	Insomnia	59/762
Blader 2010	Insomnia	21/65
Chou 2012b	Insomnia	25/230
Cortese 2015	Insomnia	31/1426
Coşkun 2010	Sleep problems	4/7
Davari‐Ashtiani 2010	Sleep problems	7/16
Döpfner 2011a, OBSEER	Initial insomnia	11/777
Döpfner 2011b	Initial insomnia	3/113
Efron 1997	Trouble sleeping	79/123
El‐Fiky 2014	Insomnia	2/31
Famularo 1987	Later sleep onset	1/10
Garg 2014	Insomnia	1/27
Gau 2006	Insomnia or trouble sleeping	15/32
Germinario 2013	Insomnia	1/9
Gerwe 2009	Difficulty falling asleep	73/263
Grcevich 2001	Sleep problems	7/75
Green 2011	Trouble sleeping	7/34
Greenhill 1983	Insomnia	2/7
Gucuyener 2003	Difficulty falling asleep	19/119
Haertling 2015	Insomnia	3/239
Hazell 2003	Sleep problems	7/10
Işeri 2007	Sleep problems	5/20
Jafarinia 2012	Insomnia	10/20
Jensen 1999 (MTA)	Insomnia	12/245
Johnson 2013	Insomnia (new onset)	12/45
Jung 2007	Insomnia	16/83
Kemner 2005 (FOCUS)	Insomnia	53/850
Khajehpiri 2014	Insomnia	44/71
Kim 2010	Insomnia	6/24
Kordon 2011	Insomnia	46/541
Kratochvil 2002	Insomnia	7/25
Lee 2007	Insomnia	24110
Li 2011	Difficulty falling asleep	9/34
Maayan 2009	Trouble sleeping	3/8
Maia 2008	Insomnia	5/31
Mayes 1994	Insomnia	9/63
McCracken 2016	Insomnia	20/61
Miller‐Horn 2008	Insomnia	2/23
Mohammadi 2004	Difficulty falling asleep	4/11
Mohammadi 2010	Trouble sleeping	9/19
Mohammadi 2012a	Difficulty falling asleep	8/23
Mohammadi 2012b	Insomnia	9/20
Montañés‐Rada 2012	Insomnia	5/40
Na 2013	Trouble sleeping	37/103
Peyre 2012a	Insomnia	21/121
Remschmidt 2005	Insomnia	3/89
Sahin 2014	Difficulty falling asleep	16/30
Sangal 2006	Insomnia	21/79
Shang 2015	Insomnia	12/66
Song 2012	Insomnia	44/116
Steele 2006	Insomnia	12/60
Su 2015	Insomnia	20/205
Tasdelen 2015	Insomnia	1/17
Thorell 2009	Difficulties falling asleep	15/79
Tomás Vila 2010b	Difficulty falling asleep	45/114
Valdizán Usón 2004	Initial insomnia	11/155
Wang 2007	Insomnia	9/166
Warshaw 2010	Difficulty falling asleep	25/260
Weiss 2007	Insomnia	13/79
Wigal 2013	Insomnia	9/39
Wigal 2015	Insomnia	24/200
Wilens 2005	Insomnia	81/229
Wilens 2006	Insomnia	16/220
Wilens 2008	Insomnia	25/127
Yatsuga 2014	Insomnia	4/50
Yildiz 2010	Difficulty sleeping	15/47
Yildiz 2011	Insomnia	7/11
Zarinara 2010	Insomnia	10/18
Zelnik 2015	Insomnia	31/128
Zeni 2007	Insomnia	21/106
Zheng 2011	Insomnia	145/1154
Zheng 2015	Insomnia	3/123
Çetin 2015	Insomnia	5/61
Depression
Atzori 2009	Vegetative symptoms	4/134
Cherland 1999	Mood symptoms or mood‐congruent psychotic symptoms	11/98
Döpfner 2011a, OBSEER	Depressed mood	13/777
Grcevich 2001	Depression	1/75
Haertling 2015	Depression	1/262
Kratochvil 2002	Depression	2/25
Na 2013	Depression	9/103
Song 2012	Depression	5/116
Valdizán Usón 2013	Depressive symptoms	7/689
Weiss 2007	Depression	5/79
Wilens 2005	Depression	6/407
Yildiz 2010	Depressive symptoms	4/47
Yildiz 2011	Depression	3/11
Disturbed sleep
Abbas 2006	Sleeping problems	4/90
Abbasi 2011	Trouble sleeping	10/20
Arabgol 2015	Disturbed sleep	4/15
Arnold 2010	Insomnia	9/150
Blader 2010	Early waking	6/65
Efron 1997	Trouble sleeping	79/123
Findling 2009	Insomnia	29/157
Galland 2010	Restless sleep	14/27
Gau 2008	Poor sleep quality	37/607
Haertling 2015	Sleep disorder	1/239
Hammerness 2009	Insomnia	7/57
Hazell 2003	Nightmares	8/10
Işeri 2007	Sleep problems	5/20
Kim 2010	Insomnia	6/27
Kim 2011	Poor sleep	8/97
Mohammadi 2004	Disturbed sleep	4/11
Montañés‐Rada 2012	Insomnia	5/40
Perera 2010	Poor sleep	13/102
Remschmidt 2005	Delayed sleep	1/105
Steele 2006	Sleep disorder	3/60
Su 2015	Poor quality sleep	1/205
Valdizán Usón 2013	Sleep disorder	33/689
Yildiz 2011	Insomnia	7/11
Zheng 2015	Poor sleep quality	3/149
Dizziness
Abbasi 2011	Dizziness	8/20
Blader 2010	Dizzy	1/65
Chou 2012b	Dizziness	9/230
Cortese 2015	Dizziness	5/1426
Davari‐Ashtiani 2010	Dizziness	0/16
Döpfner 2011b	Dizziness	1/113
Efron 1997	Dizziness	15/123
El‐Fiky 2014	Dizziness	0/31
Green 2011	Dizziness	3/14
Haertling 2015	Dizziness	1/239
Hammerness 2009	Dizziness	4/57
Hazell 2003	Dizziness	7/9
Jafarinia 2012	Dizziness	1/20
Kemner 2005 (FOCUS)	Dizziness	7/850
Kim 2010	Dizziness	2/27
Lee 2007	Dizziness	5/110
Li 2011	Dizziness	4/34
Maia 2008	Dizziness	3/39
McCracken 2016	Dizziness	6/61
Mohammadi 2004	Dizziness	2/11
Mohammadi 2012b	Dizziness	2/20
Na 2013	Dizziness	11/103
Pierce 2010	Dizziness	2/71
Sahin 2014	Dizziness	6/30
Shang 2015	Dizziness	1/66
Song 2012	Dizziness	15/116
Wang 2007	Dizziness	12/166
Wilens 2005	Dizziness	7/407
Yildiz 2010	Dizziness	2/47
Drowsiness
Barrickman 1995	Drowsiness	1/15
Efron 1997	Drowsiness	22/123
El‐Fiky 2014	Drowsiness	2/31
Garg 2014	Drowsiness	1/27
Gau 2006	Drowsiness	6/32
Germinario 2013	Drowsiness	1/9
Ghanizadeh 2012	Drowsiness	2/12
Green 2011	Drowsiness	2/14
Hazell 2003	Drowsiness	7/10
Kratochvil 2002	Somnolens	0/40
Lyon 2010	Drowsiness	2/10
Maia 2008	Drowsiness	1/39
Sahin 2014	Drowsiness	8/30
Song 2012	Somnolence	6/116
Wilens 2005	Somnolence	10/407
Wilens 2006	Somnolence	3/220
Yildiz 2011	Somnolence	1/11
Dysthymia
Haertling 2015	Dysphemia	1/239
Mohammadi 2004	Dysphemia	0/16
Emotional lability
Ardic 2014	Emotional change	22/101
Davari‐Ashtiani 2010	Emotional lability	0/16
Findling 2009	Emotional lability	5/157
Hammerness 2009	Moody	2/57
Kemner 2005 (FOCUS)	Emotional disturbance	5/850
Kordon 2011	Emotional lability	8/598
Kratochvil 2002	Emotional lability	2/25
Maayan 2009	Emotional lability	2/8
McCracken 2016	Affect lability	14/61
Silva 2004	Emotional lability	4/22
Steele 2006	Emotional lability	9/60
Warshaw 2010	Affect lability	18/260
Weiss 2007	Emotional lability	3/79
Wigal 2013	Affect lability	10/39
Wilens 2005	Emotional lability	1/229
Yildiz 2010	Emotional lability	12/47
Euphoria/hypomania
Blader 2010	Unusually happy	12/65
El‐Fiky 2014	Euphoria	0/31
Gau 2006	Euphoric	3/32
Grcevich 2001	Agitation	2/75
Green 2011	Unusually happy	0/14
Kim 2010	Euphoria	1/27
Maia 2008	Euphoric	2/39
Mohammadi 2004	Euphoria or hypomania	0/16
Sahin 2014	Ecstasy	8/30
Asthenia and fatigue
Abbasi 2011	Fatigue	13/20
Arnold 2004	Asthenia	7/76
Blader 2010	Tired + low energy	4/65
Davari‐Ashtiani 2010	Tiredness	0/16
Dittmann 2014	Fatigue	0/195
Döpfner 2011b	Fatigue	0/113
Galland 2010	Daytime sleepiness	2/27
Garg 2014	Fatigue	2/27
Haertling 2015	Asthenia	1/239
Kemner 2005 (FOCUS)	Fatigue	3/850
Lee 2007	Fatigue	5/110
McCracken 2016	Fatigue	5/61
Mohammadi 2010	Fatigue	4/19
Na 2013	Fatigue	13/103
Pierce 2010	Fatigue	3/71
Sangal 2006	Fatigue	3/79
Steele 2006	Fatigue	7/60
Wang 2007	Fatigue	5/166
Wigal 2015	Fatigue	10/200
Headache
Abbas 2006	Headache	2/90
Abbasi 2011	Headache	12/20
Akhondzadeh 2003	Headache	6/10
Akhondzadeh 2004	Headache	9/20
Altin 2013	Headache	3/25
Amiri 2008	Headache	7/27
Ardic 2014	Headache	16/101
Arnold 2004	Headache	24/76
Arnold 2010	Headache	12/150
Atzori 2009	Headache	6/129
Barrickman 1995	Headache	1/15
Berek 2011	Headache	15/762
Blader 2010	Headache	1/65
Chou 2012b	Headache	7/230
Cortese 2015	Headache	62/1426
Dirksen 2002	Headache	17/287
Dittmann 2014	Headache	1/195
Döpfner 2011a, OBSEER	Headache	9/777
Döpfner 2011b	Headache	8/113
Efron 1997	Headache	30/123
El‐Fiky 2014	Headache	4/31
Findling 2009	Headache	54/157
Galland 2010	Morning headache	3/27
Garg 2014	Headache	4/27
Gau 2006	Headache	11/32
Gau 2008	Headache	21/607
Gerwe 2009	Headache	15/263
Goez 2012	Headache	4/28
Golubchik 2011	Headache	2/9
Green 2011	Headache	8/14
Greenberg 1987	Headache	1/49
Greenhill 1983	Headache	2/7
Gucuyener 2003	Headache	14/119
Guerreiro 1996	Headache	2/22
Haertling 2015	Headache	2/239
Hammerness 2009	Headache	14/57
Hazell 2003	Headache	8/10
Hulvershorn 2012	Headache	1/25
Işeri 2007	Headache	5/20
Jafarinia 2012	Headache	10/20
Jung 2007	Headache	8/83
Kemner 2005 (FOCUS)	Headache	33/850
Khajehpiri 2014	Headache	7/71
Kim 2010	Headache	3/27
Kordon 2011	Headache	14/541
Kratochvil 2002	Headache	13/25
Lee 2007	Headache	16/110
Lee 2014	Headache	6/100
Li 2011	Headache	3/34
Maayan 2009	Headache	1/11
Maia 2008	Headaches	4/39
Mayes 1994	Headache	3/63
McCracken 2016	Headache	23/61
Miller‐Horn 2008	Headache	1/23
Mohammadi 2004	Headache	7/11
Mohammadi 2010	Headache	15/19
Mohammadi 2012a	Headache	4/23
Mohammadi 2012b	Headache	9/20
Na 2013	Headache	32/103
Perera 2010	Headache	13/102
Peyre 2012a	Headache	43/121
Pierce 2010	Headache	6/71
Remschmidt 2005	Headache	2/105
Sahin 2014	Headache	14/30
Sangal 2006	Headache	12/79
Schulz 2010	Headache	9/145
Shang 2015	Headache	14/66
Silva 2004	Headache	4/22
Song 2012	Headache	30/116
Steele 2006	Headache	14/60
Su 2015	Headache	4/205
Tasdelen 2015	Headache	1/17
Thorell 2009	Headache	6/79
Valdizán Usón 2004	Headache	2/155
Valdizán Usón 2013	Headache	11/689
Wang 2007	Headache	16/166
Warshaw 2010	Headache	23/260
Weiss 2007	Headache	10/79
Wigal 2013	Headache	7/39
Wigal 2015	Headache	35/200
Wilens 2005	Headache	123/229
Wilens 2006	Headache	25/220
Wilens 2008	Headache	27/127
Yatsuga 2014	Headache	7/50
Yildiz 2010	Headache	27/47
Yildiz 2011	Headache	3/11
Zarinara 2010	Headache	11/18
Zelnik 2015	Headache	107/128
Zheng 2011	Headache	143/1154
Çetin 2015	Headache	2/61
Increased need to sleep
Blader 2010	Trouble waking	1/65
Galland 2010	Hard to wake + difficult to wake	14/27
Mohammadi 2004	Increased need to sleep	5/11
Mohammadi 2012a	Sleepiness	4/23
Na 2013	Somnolence	8/103
Pierce 2010	Somnolence	2/71
Wang 2007	Somnolence	6/166
Zarinara 2010	Somnolence	3/19
Involuntary movements
Balázs 2011	Involuntary movements after methylphenidate treatment	9/34
Berek 2011	Muscle contractions, involuntary	34/762
Blader 2010	Shaking + tremor	4/65
Galland 2010	Restless legs	2/27
Kordon 2011	Muscle contraction, involuntary	13/541
Kratochvil 2002	Hyperkinesia	2/25
Lee 2014	Convulsion	4/100
Irritability
Abbasi 2011	Irritability	18/20
Amiri 2008	Irritability	6/27
Ardic 2014	Irritability	30/101
Atzori 2009	Irritability	9/129
Barrickman 1995	Irritability	1/15
Blader 2010	Irritability	16/65
Cortese 2015	Irritabillity	67/1426
Efron 1997	Irritable	100/123
El‐Fiky 2014	Irritable	6/31
Findling 2009	Irritability	20/157
Garg 2014	Irritability	2/27
Gau 2006	Irritable	7/32
Green 2011	Irritability	2/14
Greenhill 1983	Irritability	4/7
Hazell 2003	Irritability	3/10
Işeri 2007	Irritability	3/20
Jensen 1999 (MTA)	Irritability	10/245
Johnson 2013	Irritability	23/45
Kemner 2005 (FOCUS)	Irritability	7/850
Khajehpiri 2014	Irritability	25/71
Maayan 2009	Irritability	1/8
Maia 2008	Irritability	10/39
Mayes 1994	Irritability	18/63
McCracken 2016	Irritability	12/61
Mohammadi 2012a	Irritability	10/23
Na 2013	Irritable	16/121
Sangal 2006	Irritability	12/79
Silva 2004	Irritability	3/22
Song 2012	Irritability	9/116
Tasdelen 2015	Irritability	5/17
Valdizán Usón 2004	Irritability	4/155
Wang 2007	Irritability	10/166
Warshaw 2010	Irritability	15/260
Wigal 2015	Irritability	11/200
Yildiz 2010	Irritability	16/47
Nervousness
Arabgol 2015	Nervousness	5/15
Berek 2011	Nervousness	17/762
Jafarinia 2012	Nervousness	5/20
Kordon 2011	Nervousness	13/541
Kratochvil 2002	Nervousness	4/25
Lee 2007	Nervousness	2/110
Mohammadi 2010	Nervousness	14/19
Na 2013	Nervousness	7/103
Song 2012	Nervousness	9/116
Steele 2006	Nervousness	9/60
Weiss 2007	Nervousness	14/79
Wilens 2006	Nervousness	6/220
Yildiz 2011	Nervousness	9/11
Çetin 2015	Nervousness	2/61
Nightmares
Blader 2010	Nightmares	2/65
El‐Fiky 2014	Nightmares	1/31
Gau 2006	Nightmares	8/32
Green 2011	Nightmares	1/14
Khajehpiri 2014	Nightmares	3/71
Kim 2010	Nightmares	1/27
Maia 2008	Nightmares	1/31
Sahin 2014	Nightmares	4/30
Silva 2004	Nightmares	1/22
Song 2012	Nightmares	10/116
Tomás Vila 2010b	Nightmares	12/114
Restlessness and agitation
Blader 2010	Restlessness	3/65
Davari‐Ashtiani 2010	Restlessness	4/16
Dittmann 2014	Agitation	1/195
Döpfner 2011b	Restlessness	1/113
Grcevich 2001	Agitation	2/75
Haertling 2015	Agitation	2/239
Khajehpiri 2014	Agitation	16/71
Lee 2014	Agitation	6/100
Mohammadi 2010	Restlessness	8/19
Perera 2010	Restlessness	5/102
Sahin 2014	Restlessness	9/30
Steele 2006	Agitation	8/60
Valdizán Usón 2013	Physical activity modifications	16/689
Zarinara 2010	Restlessness	5/19
Sadness
Abbasi 2011	Sadness	9/20
Amiri 2008	Sadness	6/27
Barrickman 1995	Low mood	1/15
Blader 2010	Crying + sadness	17/65
Davari‐Ashtiani 2010	Sadness	3/16
Efron 1997	Sadness or unhappiness	69/123
El‐Fiky 2014	Sad	3/31
Garg 2014	Sadness	0/27
Gau 2006	Sadness	14/32
Green 2011	Sadness	7/14
Hammerness 2009	Sad	1/57
Hazell 2003	Sad	5/10
Işeri 2007	Sadness	2/20
Jensen 1999 (MTA)	Tearfulness	6/245
Johnson 2013	Sadness	18/45
Kemner 2005 (FOCUS)	Crying	13/850
Maia 2008	Sad	4/31
Mohammadi 2010	Sadness	4/19
Mohammadi 2012a	Sadness	2/23
Perera 2010	Sadness	13/102
Sahin 2014	Sadness	9/30
Stares
Blader 2010	Stares into space	3/65
El‐Fiky 2014	Stares a lot	8/31
Hazell 2003	Stares	6/10
Maia 2008	Stares a lot or daydreams	7/31
Excessive talking
Blader 2010	Overly talkative	8/65
Hazell 2003	Talks too much	5/10
Khajehpiri 2014	Speaking more	6/71
Taciturnity ('talking too little')
Blader 2010	Less talkative	4/65
El‐Fiky 2014	Talk less	2/31
Green 2011	Talking little	6/14
Maia 2008	Talk less	9/31
Tics
Ardic 2014	Tics	3/101
Atzori 2009	Tics	2/129
Blader 2010	Tics	3/65
Cortese 2015	Tics	27/1426
Davari‐Ashtiani 2010	Tics	1/16
Döpfner 2011a, OBSEER	Tics	100/777
Döpfner 2011b	Tics	1/113
Efron 1997	Tics	35/123
El‐Fiky 2014	Tics or involuntary movements	0/31
Findling 2009	Tics	0/157
Gau 2006	Tics	6/32
Germinario 2013	Tics	1/9
Golubchik 2011	Motor tics exacerbation	1/9
Grcevich 2001	Motor tics	1/75
Green 2011	Tics	0/14
Gucuyener 2003	Motor tics	2/119
Işeri 2007	Tics	3/20
Johnson 2013	Tics (new onset)	1/45
Khajehpiri 2014	Tics	18/71
Kim 2010	Tics	3/27
Kim 2011	Tics	19/97
Lakic 2012	Tics	3/61
Lee 2007	Tics	6/110
Miller‐Horn 2008	Tics	2/23
Mohammadi 2004	Tics	0/11
Mohammadi 2012a	Tics	1/23
Mohammadi 2012b	Tics	4/20
Remschmidt 2005	Tics	7/89
Sahin 2014	Tics	2/30
Shang 2015	Tics	1/66
Song 2012	Tics	7/116
Su 2015	Tourette disorder	6/205
Tasdelen 2015	Tics	1/17
Valdizán Usón 2004	Tics	1/155
Varley 2001	Tics	31/374
Wilens 2005	Twitching	40/229
Yildiz 2010	Tics	1/47
Yildiz 2011	Tics	2/11
Çetin 2015	Tics	1/16
Isolation and lack of interest in others
Blader 2010	Lack of interest	6/65
Efron 1997	Uninterested in others	39/123
El‐Fiky 2014	Uninterested in others	2/31
Green 2011	Uninterested	4/14
Hazell 2003	Uninterested	6/10
Khajehpiri 2014	Isolation	6/71
Maia 2008	Uninterested others	6/31
Perera 2010	Social withdrawal	6/102
Sahin 2014	Being in own world	5/30
Yildiz 2010	Introversion (maybe isolation)	5/47
'Zombie like' demeanour
Davari‐Ashtiani 2010	Zombie like	3/16
Jensen 1999 (MTA)	Zombie like	18/245
Wilens 2005	Apathy	4/407
Somnolence
Chou 2012b	Somnolence	1/230
Khajehpiri 2014	Somnolence	5/71
McCracken 2016	Somnolence	3/61
Na 2013	Somnolence	8/103
Shang 2015	Somnolence	1/66
Wang 2007	Somnolence	6/166
Weiss 2007	Somnolence	7/79
Wilens 2005	Somnolence	1/229
Yildiz 2011	Somnolence	1/11
Obsession
Cortese 2015	Obsessive behaviour	6/1426
Khajehpiri 2014	Obsession	1/71
Çetin 2015	Obsession	2/32
Mood disorder
Cortese 2015	Mood disorder	49/1426
Haertling 2015	Emotional disorder of childhood	1/239
Confusional state
Haertling 2015	Confusional state	1/262
Zelnik 2015	Sense of dopiness	13/128
Sleep disorder
Dittmann 2014	Sleep disorder	6/195
Döpfner 2011a, OBSEER	Sleep disorder	9/777
Su 2015	Sleep disorder	26/239
Propensity to cry
El‐Fiky 2014	Prone to cry	4/31
Sahin 2014	Sudden crying	12/30
Sedation
McCracken 2016	Sedation	4/61
Mohammadi 2010	Sedation	4/19
Daytime sleepiness
Galland 2010	Daytime sleepiness	2/27
Tomás Vila 2010b	Datime sleepiness	2/114
Dysphoria
Atzori 2009	Dysphoria	2/134
Logorrhoea
Atzori 2009	Loggorrhoea	1/129
Impaired concentration
Berek 2011	Impaired concentration	14/822
Difficulty waking up
Galland 2010	Difficult to wake up	7/28
Urinary incontinence
Garg 2014	Urinary incontinence	1/32
Paralysis
Haertling 2015	Paralysis	1/239
Affective disorder
Haertling 2015	Affective disorder	1/239
Jumbled thoughts
Hammerness 2009	Jumbled thoughts	1/154
Bulimia
Khajehpiri 2014	Bulimia	5/71
Sleep late
Khajehpiri 2014	Sleeping late	22/71
Tooth grinding
Khajehpiri 2014	Tooth grinding	3/71
Tremor
Khajehpiri 2014	Tremor	2/71
Stuttering
Khajehpiri 2014	Stuttering	4/71
Flushing
Khajehpiri 2014	Flushing	9/71
Apathy
Kordon 2011	Apathy	6/541
Abnormal behaviour
Lee 2014	Abnormal behaviour	5/100
Stereotypies
Mohammadi 2004	Stereotypies	0/16
Quietness
Sahin 2014	Quietness	6/30
EEG changes
Schmidt 2002	Pathologic	25/124
Did not like themselves
Thorell 2009	Does not like him‐ or herself	10/79
Sleep walking
Tomás Vila 2010b	Sleep walking	2/114
Personality and behaviour disorders
Valdizán Usón 2013	Personality and behavior disorders	14/633
Vertigo
Yildiz 2011	Vertigo	3/11