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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Rashid 2007.

Methods A patient report of intensified somatic hallucinations during dose increase of methylphenidate treatment at the hospital
Participants Diagnosis of ADHD: DSM‐IV (subtype: unknown)
Age: 10 years old
IQ: > 70
Sex: male
Ethnicity: unknown
Country: USA
Comorbidity: chronic pattern of somatisation
Comedication: unknown
Methylphenidate‐naïve: no. OROS methylphenidate, 36 mg/day, ≥ 2 years
Sociodemographics: history of several foster placements, now adopted
Interventions Methylphenidate dose: regular‐release methylphenidate, 10 mg, twice daily, then titrated to regular‐release methylphenidate, 15 mg, twice daily, 2 days
Treatment compliance: not stated
Outcomes Serious adverse events:
Hallucinations
Regular‐release methylphenidate, 10 mg, twice daily
Regular‐release methylphenidate, 15 mg, twice daily, 2 days: somatic hallucinations
Discontinuation of methylphenidate: complete resolution of the psychotic phenomena within 2 days
Follow‐up 1 year later: no unexplained somatic complaints
Notes Funding/vested interest: no financial relationships to disclose
Authors' affiliations: no affiliations to pharmaceutical companies stated
Key conclusions of the study authors: here we describe a case of a 10‐year‐old boy with ADHD with a chronic pattern of somatisation, which evolved into overt somatic hallucinations with an increase in the methylphenidate dose. This pattern of somatisation was retrospectively recognised as partial somatic hallucinations
Supplemental information regarding ADHD diagnostic criteria and IQ received through personal email correspondence with the authors in October 2013 (Rashid 2013 [pers comm])