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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Spencer 1992.

Methods A cohort study of methylphenidate use for 14.2 (SD 10.7) months
Participants Number of participants screened: not stated
Number of participants included: 29
Number followed up: 29
Number of withdrawals: not stated
Diagnosis of ADHD: DSM‐III‐R (subtype: not stated)
Age: mean 7.8 SD 2.4
IQ: not stated
Sex: not stated
Methylphenidate‐naïve: not stated
Ethnicity: not stated
Country: USA
Comorbidity: not stated
Comedication: not stated
Sociodemographics: not stated
Inclusion criteria:
 1. DSM‐III‐R diagnosis of ADHD
Interventions Methylphenidate type: immediate release
Mean methylphenidate dosage: 31.4 (SD 17.6) mg (1 mg/kg SD 0.5)
Administration schedule: not stated
Duration of intervention: 14.2 (SD 10.7) months
Treatment compliance: not stated
Outcomes Non‐serious adverse events:
Assessment of growth deficits: simple growth deficit, percent deficit, change in cumulative frequency percentiles, percent change, standardised height deficit, deficits in growth velocity
Malnutrition index
Notes Sample calculation: not stated
 Ethics approval: not stated
 Funding/vested interest: not stated
 Authors' affiliations: not stated
Key conclusions of the study authors: although there were statistically significant weight deficits in children treated with both desipramine and methylphenidate compared with normal controls, only those treated with methylphenidate sustained height deficits that attained statistical significance
Exclusion of methylphenidate non‐responders/children who have previously experienced adverse events on methylphenidate: not stated
Supplemental information requested through personal email correspondence with the authors in September and October 2013. No reply