Strandell 2007.
Methods | A series of spontaneously reported cases of suicidal and self‐damaging behaviour from VigiBase | |
Participants | Number of cases reported: 116 Diagnostic criteria not stated, nor subtype Age(range): 5‐17 years old IQ: not stated Sex: not stated Ethnicity: not stated Country: not stated Comorbidity: 78 were depressed, otherwise not stated Comedication: in 33 cases methylphenidate and atomoxetine were co‐reported. 17 depressed patients were on antidepressants, and 42 were on antidepressants (without depression) ‐ (not clear if they were on atomoxetine or methylphenidate) Sociodemographics: not stated |
|
Interventions | Methylphenidate type: not stated Methylphenidate dosage: not stated Administration schedule: not stated Duration of intervention: not stated Treatment compliance: not stated |
|
Outcomes |
Serious adverse events: Depression suicidal Intentional overdose Intentional self‐injury Non‐accidental injury Suicidal tendency Suicide Suicide attempt Thoughts of self‐harm |
|
Notes | Ethics approval: not stated Funding/vested interest/authors' affiliations: not stated Key conclusions of the study authors: the number of reports with suicidal behaviour in children and adolescents raises concern. The reports do not only imply possible suicidal behaviour: young patients actually commit suicide Comments from the review authors: this case‐series is based on a database of spontaneously reported adverse events. Therefore, some of these cases might have been reported in other case‐reports Supplemental information, specifically asking for full‐text article and additional information, requested through email correspondence with the authors in November 2013. No reply |