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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Tomás Vila 2010a.

Methods A patient report of visual hallucinations during methylphenidate treatment
Participants Diagnosis of ADHD: DSM‐IV (subtype: combined)
Age: 10 years old
IQ: above 70
Sex: male
MPH‐naïve: no
Ethnicity: not stated
Country: Spain
Comorbidity: none stated
Comedication: not stated
Sociodemographics: lives with his grandmother
Interventions Methylphenidate type: 50% immediate release and 50% extended release
Methylphenidate dose: 30 mg/day (1 mg/kg/day)
Administration schedule: not stated
Duration of treatment: 2 weeks
Treatment compliance: not stated
Outcomes Serious adverse events:
After 2 weeks of 50% immediate release and 50% extended release methylphenidate: visual hallucinations (insects on hands, feet, abdomen and thorax) with associated itching, initiated 2 hours after ingestion and ceased 5 hours after
Discontinuation of methylphenidate and initiation of risperidone: no visual hallucinations
No readministration of methylphenidate due to ethical reasons
Notes Key conclusions of the study authors: this is the first patient report of visual hallucinations caused by 50% immediate release, 50% extended release methylphenidate, which is no wonder when you consider that the preparation has been marketed recently
Funding/vested interests/authors' affiliations: not stated
Supplemental information regarding diagnostic criteria and IQ received through personal email correspondence with the authors in September 2013 (Tomás 2013 [pers comm])