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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Vashi 2011.

Methods A patient report on allergic contact dermatitis caused by methylphenidate transdermal system
Participants Diagnosis of ADHD: DSM‐IV (subtype: not known)
Age: 9 years old
IQ: above 70
Sex: female
Ethnicity: not stated
Country: USA
Comorbidity: none
Comedication: not stated
Sociodemographics: not stated
Interventions Methylphenidate type: transdermal system
Methylphenidate dosage: not known
Administration schedule: not stated
Duration of intervention: 8 months
Treatment compliance: not stated
Outcomes Non‐serious adverse events:
Allergic contact dermatitis: after 8 months of using a methylphenidate patch the patient presented with pruritic dermatitis. She had itchy, burning, red lesions. Symptoms began on her hip at the area of patch placement, then progressively spread to her arms, legs, abdomen, and back
Methylphenidate discontinued: symptoms lasted for 2 months. First and second patch test. Re‐tested with methylphenidate patch: 9 days after the first test the patient presented with recall reaction, characterised by a return of the original pruritic dermatitis to her entire back, similar to the eruption that had occurred months previously after therapeutical use of methylphenidate patch
Avoidance of methylphenidate patches: symptom‐free
Notes Key conclusions of study authors: this is the first reported case of allergic contact dermatitis caused by methylphenidate present within the transdermal system
Supplemental information regarding diagnosis and IQ received through personal email correspondence with first author in August 2013 (Vashi 2013 [pers comm])