Vashi 2011.
Methods | A patient report on allergic contact dermatitis caused by methylphenidate transdermal system | |
Participants | Diagnosis of ADHD: DSM‐IV (subtype: not known) Age: 9 years old IQ: above 70 Sex: female Ethnicity: not stated Country: USA Comorbidity: none Comedication: not stated Sociodemographics: not stated |
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Interventions | Methylphenidate type: transdermal system Methylphenidate dosage: not known Administration schedule: not stated Duration of intervention: 8 months Treatment compliance: not stated |
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Outcomes |
Non‐serious adverse events: Allergic contact dermatitis: after 8 months of using a methylphenidate patch the patient presented with pruritic dermatitis. She had itchy, burning, red lesions. Symptoms began on her hip at the area of patch placement, then progressively spread to her arms, legs, abdomen, and back Methylphenidate discontinued: symptoms lasted for 2 months. First and second patch test. Re‐tested with methylphenidate patch: 9 days after the first test the patient presented with recall reaction, characterised by a return of the original pruritic dermatitis to her entire back, similar to the eruption that had occurred months previously after therapeutical use of methylphenidate patch Avoidance of methylphenidate patches: symptom‐free |
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Notes |
Key conclusions of study authors: this is the first reported case of allergic contact dermatitis caused by methylphenidate present within the transdermal system Supplemental information regarding diagnosis and IQ received through personal email correspondence with first author in August 2013 (Vashi 2013 [pers comm]) |