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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Woolley 2003.

Methods A patient report of obsessive‐compulsive disorder (OCD) emerging during methylphenidate treatment
Participants Diagnosis of ADHD: ICD‐10 (subtype: not stated)
Age: 11 years old
IQ: normal
Sex: male
Ethnicity: not stated
Country: UK
Comorbidity: obsessive‐compulsive disorder
Comedication: Risperidone (1 mg/day)
Sociodemographics: not stated
Interventions Methylphenidate type: immediate release
Methylphenidate dosage: 40 mg/day
Administration schedule: not stated
Duration of treatment: more than 15 months
Treatment compliance: not stated
Outcomes Non‐serious adverse events:
Obsessions and compulsions with anxiety (DSM‐IV diagnosis of OCD). Washing his hands excessively, accompanied by checking rituals, reassurance seeking, and emetophobia. When methylphenidate was withdrawn the OCD symptoms decreased rapidly but increased when methylphenidate was reintroduced
Notes Key conclusions of the study authors: obsessive‐compulsive disorder (OCD) may emerge with stimulant treatment for attention deficit hyperactivity disorder (ADHD). We report a case of OCD worsening with methylphenidate treatment but not with dexamphetamine
Funding/vested interest/authors affiliation: not stated
Supplemental information regarding ADHD diagnosis and IQ received through personal email correspondence with the authors in October 2013 (Heyman 2013 [pers comm])