Woolley 2003.
Methods | A patient report of obsessive‐compulsive disorder (OCD) emerging during methylphenidate treatment | |
Participants | Diagnosis of ADHD: ICD‐10 (subtype: not stated) Age: 11 years old IQ: normal Sex: male Ethnicity: not stated Country: UK Comorbidity: obsessive‐compulsive disorder Comedication: Risperidone (1 mg/day) Sociodemographics: not stated |
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Interventions | Methylphenidate type: immediate release Methylphenidate dosage: 40 mg/day Administration schedule: not stated Duration of treatment: more than 15 months Treatment compliance: not stated |
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Outcomes |
Non‐serious adverse events: Obsessions and compulsions with anxiety (DSM‐IV diagnosis of OCD). Washing his hands excessively, accompanied by checking rituals, reassurance seeking, and emetophobia. When methylphenidate was withdrawn the OCD symptoms decreased rapidly but increased when methylphenidate was reintroduced |
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Notes |
Key conclusions of the study authors: obsessive‐compulsive disorder (OCD) may emerge with stimulant treatment for attention deficit hyperactivity disorder (ADHD). We report a case of OCD worsening with methylphenidate treatment but not with dexamphetamine Funding/vested interest/authors affiliation: not stated Supplemental information regarding ADHD diagnosis and IQ received through personal email correspondence with the authors in October 2013 (Heyman 2013 [pers comm]) |