Zhang 2010.
| Methods | A case‐control study of methylphenidate use for 2‐4 years | |
| Participants | Number of participants screened: not stated Number of participants included: 175 Number included as cases: methylphenidate 126; controls (no intervention) 29 Number followed up in each arm: methylphenidate 46; controls 2 Number of withdrawals in each arm: methylphenidate 98; controls 27 Diagnosis of ADHD: DSM‐IV (subtype: combined (74.65%), hyperactive‐impulsive (8.9%), inattentive (16.43%)) Age: mean 7.42 years old (range 6‐9.8) IQ: not stated Sex: 126 males, 20 females Methylphenidate‐naïve: not stated Ethnicity: not stated Country: China Comorbidity: oppositional defiant disorder (39.73%), conduct disorder (4.79%), learning disorder (8.22%), tics (4.79%) Comedication: not stated Sociodemographics: not stated Inclusion criteria:
Exclusion criteria:
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| Interventions | Methylphenidate type: immediate release Mean methylphenidate dosage: 0.27‐0.64 mg/kg Administration schedule: 2 time points (mornings and afternoons) Duration of intervention: 2‐4.8 years Treatment compliance: not stated |
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| Outcomes | Non‐serious adverse events: Height Weight BMI | |
| Notes | Sample calculation: not stated Ethics approval: not stated Funding/vested interest: not stated Authors' affiliations: Department of Paediatrics, First Affiliated Hospital, Sun Yat‐sen University, Guangzhou, P. R. China Key conclusions of the study authors: methylphenidate inhibits linear growth of children, but it is correlated to methylphenidate treatment length; there was no influence on weight; there was no differences on BMI Exclusion of methylphenidate non‐responders/children who have previously experienced adverse events on methylphenidate: not stated Supplemental information requested through personal email correspondence with the authors in June 2014. Email sent twice but no answer received |
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