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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Abbas 2006.

Methods A cohort study with 2 study samples (N = 60 and N = 30) where participants were part of a 6‐month audit regarding the use of methylphenidate and to determine if the NICE guidelines were followed
Participants Number of participants screened: 420
Number of participants included: 90
Number of participants followed up: not stated
Number of withdrawals: not stated
Sex: 85 males, 5 females
Diagnosis of ADHD: DSM‐IV (subtype: not stated)
Age: mean 10 years old
IQ: none with intellectual disability
Methylphenidate‐naïve: not stated
Ethnicity: not stated
Country: UK
Setting: not stated
Comorbidity: 28.8% general learning difficulties, 21% sleeping problems, 28.8% mental health problems
Comedication: not stated
Sociodemographics: not stated
Inclusion criteria:
  1. Children with a diagnosis of ADHD according to DSM‐IV who were prescribed MP after October 2000

Interventions Methylphenidate dosage: most were treated with Ritalin
Administration schedule: not stated
Duration of intervention: 6 months
Treatment compliance: not stated
Outcomes Non‐serious adverse events:
12% reported side effects on methylphenidate, most were transient
In 3 cases, medication was stopped due to side effects
Notes Sample calculation: not stated
Any withdrawals due to adverse events: for 3 patients the side effects resulted in medication stop. 2 patients stopped because of headaches and 1 because of hair loss
Ethics approval: not stated
Funding: none
Vested interest/authors' affiliations: not stated
Key conclusions of the study authors: the guidelines were followed, but not fully. However this was improved significantly in the second part due to increased professional awareness about ADHD because we held many seminars on this subject. The mental health team worked more closely than before with community paediatricians via joint ADHD clinics with child and adolescent psychiatrists. Families were getting better support via the ADHD family project which was jointly funded by health, education, and social services. The audits lead to a better provision of services for children with ADHD via specialist ADHD clinics
Comments from the review authors: the reference was a poster, and no full text article has been published on the subject
Exclusion of methylphenidate non‐responders/children who have previously experienced adverse events on methylphenidate: no
Supplemental information regarding study information received through personal email correspondence with the authors in December 2013 (DeSoysa 2013 [pers comm])