Agarwal 2008.
Methods | A patient report of the combination of atomoxetine and methylphenidate in the treatment of ADHD | |
Participants | Diagnosis of ADHD: DSM‐III‐R/DSM‐I (subtype: combined) Age: 8 years old IQ: normal (attends school) Sex: male Methylphenidate naïve: no Ethnicity: not stated Country: India Comorbidity: not stated Comedication: not stated. No atomoxetine (in the period relevant for this review) Sociodemographics: not stated |
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Interventions | Immediate release methylphenidate gradually increased to 50 mg/day Administration schedule: 3‐4 divided dosages Duration of intervention: 6 months Treatment compliance: not stated |
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Outcomes |
Non‐serious adverse events: Decreased appetite and delayed sleep onset |
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Notes | Key conclusions of the study authors: the combination of atomoxetine and methylphenidate may be used more often in patients who are not able to tolerate high doses of methylphenidate or develop tolerance to it |