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. 2018 May 10;2018(5):CD012069. doi: 10.1002/14651858.CD012069.pub2

Alpaslan 2015.

Methods A patient report of stuttering associated with the use of methylphenidate
Participants Diagnosis of ADHD: DSM‐5 (subtype: predominantly hyperactive‐impulsive)
Age: 7 years old
IQ: 94
Sex: male
Methylphenidate naïve: yes
Ethnicity: white/Turkish
Country: Turkey
Comorbidity: none
Comedication: none
Sociodemographics: both parents had advanced no further than elementary school. The parents' history was unremarkable
Interventions Short‐acting methylphenidate 10 mg/daily
Administration schedule: not stated
Duration of treatment: 4 weeks
Treatment compliance: good according to regular visits record
Outcomes Non‐serious adverse events:
10 days after beginning short‐acting methylphenidate treatment, the client began to stutter. Treatment was stopped. 1 week later, the patient's speech was back to normal. 4 weeks later atomoxetine treatment was started with no reoccurrence of stuttering
Notes Key conclusions of the study authors: evidence for stuttering associated with the use of short‐acting methylphenidate is presented. Clinicians should be aware that an additional adverse effect of methylphenidate may be a beginning of a stutter
Funding/vested interest: the authors received no financial support for the research and/or authorship of this article. The authors report no conflicts of interest
Supplemental information regarding IQ, ethnicity and treatment compliance received through personal email correspondence with the authors in April 2016 (Alpaslan 2016 [pers comm])