Arun 2014.

Methods	2 patient reports of suicidal ideation during methylphenidate treatment
Participants	Case 1 Diagnosis of ADHD: DSM‐IV TR (subtype: combined) Age: 8 years old IQ: > 70 Sex: male Ethnicity: Hindu Country: India Comorbidity: none Comedication: none Sociodemographics: living in joint family Case 2 Diagnosis of ADHD: DSM‐IV TR (subtype: combined) Age: 7 years old IQ: average Sex: male Ethnicity: Hindu Country: India Comorbidity: none Comedication: none Sociodemographics: living in nuclear family
Interventions	Case 1 Immediate release methylphenidate dosage: 5 mg/day Administration schedule: once daily in the morning Duration of treatment: 2 days Treatment compliance: not stated Case 2: Methylphenidate type: not stated Methylphenidate dosage: 10 mg/day Administration schedule: once daily Duration of treatment: 12 days Treatment compliance: not stated
Outcomes	Serious adverse events Suicidal ideation Non‐serious adverse events Impairment in sleep onset for 1 night
Notes	Key conclusions of the study authors: depressed mood or affective symptoms may occur as an adverse effect during Methylphenidate treatment, and impulsivity may result in attempted suicide even in ADHD children without depression. In view of the current findings and existing literature, clinicians need to be alert to the adverse effects of methylphenidate during examination of every case. Equally important is ensuring that the patients' parents and teachers of the patients are appropriately educated regarding potential adverse effects of methylphenidate Comments from the study authors: there was no depressive symptoms reported along with it, and the ideation could not be explained on the basis of impulsivity either Funding/vested interest: nil, none otherwise declared Authors' affiliations: Department of Psychiatry, Government Medical College and Hospital, Chandigarh, India Supplemental information received through personal email correspondence with the authors in September 2014 (Arun 2014 [pers comm])