Comparison 1. Processed EEG versus clinical signs guided anaesthesia (available data analysis).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 POD	3	2197	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.59, 0.85]
2 POCD at one week	3	1989	Risk Ratio (M‐H, Fixed, 95% CI)	0.84 [0.69, 1.02]
3 POCD at 12 weeks	3	2051	Risk Ratio (M‐H, Fixed, 95% CI)	0.71 [0.53, 0.96]