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. 2018 May 9;2018(5):CD009069. doi: 10.1002/14651858.CD009069.pub3
  Nona‐valent vaccine (Luxembourg 2015)
Manufacturer Merck, Sharp & Dome (Merck & Co, Whitehouse Station, NJ, USA)
Antigens L1 VLPs of HPV6 (30 μg), HPV11 (40 μg), HPV16 (60 μg), HPV18 (40 mg),
HPV31 (20 μg), HPV33 (20 μg), HPV45 (20 μg), HPV52 (20 μg)
and HPV58 (20 μg).
Vaccination schedule 3 doses: at day 1, month 2 and month 6
Adjuvant 500 μg amorphous aluminium hydroxyl‐phosphate sulphate
Trade name Gardasil‐9
Produced by recombinant
technology using
Saccharomyces cerevisae (baker’s yeast)