6.

Acute rejection: glucocorticosteroid avoidance or withdrawal versus glucocorticosteroid containing immunosuppression. Trial Sequential Analysis of the effect of glucocorticosteroid avoidance or withdrawal versus glucocorticosteroid‐containing immunosuppression on acute rejection based on 16 trials with 1347 participants. The diversity‐adjusted required information size (DARIS) was calculated on the basis of type I error of 5%, type II error of 20% and risk reduction of 20%, and information size was adjusted for diversity (0%). The cumulative Z‐curve does not cross trial sequential monitoring boundaries, and the required information size was not reached.