Skip to main content
. 2018 Apr 9;2018(4):CD007606. doi: 10.1002/14651858.CD007606.pub4
Database Time span Search strategy
The Cochrane Hepato‐Biliary Group Controlled Trials Register May 2017 ((liver OR hepat*) AND (transplant* OR graft*)) AND (glucocorticosteroid* OR corticosteroid* OR steroid* OR gluco‐corticoid* OR cortico‐steroid* OR methylpredniso* OR methyl‐predniso* OR predniso* OR dexamethaso* OR dexa‐methaso* or monotherapy*) AND (immunosuppres* or tacrolimus* or mycopheno* or MMF* or (monoclonal adj3 antibod*) or mab* or daclizumab* or basiliximab* or cyclosporin* or ciclosporin* or calcineurin inhibitor* or calcineurin antagonist* or purine inhibitor* or purine antagonist* or sirolimus* or rapamycin* or everolimus* or methotrexate* or azathioprine* or muromonab* or orthoclon* or OKT3* or anti‐CD3* or antithymocyte* or ATG* or anti‐IL2* or anti‐CD52* or campath* or FK506* or steroid‐free* or corticosteroid‐free* or glucocorticoid‐free* or glucocorticosteroid‐free* or steroid‐sparing* or corticosteroid‐sparing* or glucocorticoid‐sparing* or glucocorticosteroid‐sparing* or steroid‐avoid* or corticosteroid‐avoid* or glucocorticoid‐avoid* or glucocorticosteroid‐avoid* or steroid‐taper* or corticosteroid‐taper* or glucocorticoid‐taper* or glucocorticosteroid‐taper* or steroid‐withdraw* or corticosteroid‐withdraw* or glucocorticoid‐withdraw* or glucocorticosteroid‐withdraw* or steroid‐eliminat* or corticosteroid‐eliminat* or glucocorticoid‐eliminat* or glucocorticosteroid‐eliminat* or steroid‐minimi* or corticosteroid‐minimi* or glucocorticoid‐minimi* or glucocorticosteroid‐minimi*)
Cochrane Central Register of Controlled Trials (CENTRAL) Issue 5 of 12 2017 #1 MeSH descriptor: [Liver Transplantation] explode all trees
#2 ((liver or hepat*) and (transplant* or graft*))
#3 #1 or #2
#4 MeSH descriptor: [Steroids] explode all trees
#5 MeSH descriptor: [Adrenal Cortex Hormones] explode all trees
#6 MeSH descriptor: [Methylprednisolone] explode all trees
#7 MeSH descriptor: [Prednisone] explode all trees
#8 MeSH descriptor: [Glucocorticoids] explode all trees
#9 MeSH descriptor: [Dexamethasone] explode all trees
#10 glucocorticosteroid* or corticosteroid* or steroid* or gluco‐corticoid* or cortico‐steroid* or methylpredniso* or methyl‐predniso* or predniso* or dexamethaso* or dexa‐methaso* or monotherapy*
#11 #4 or #5 or #6 or #7 or #8 or #9 or #10
#12 MeSH descriptor: [Immunosuppression] explode all trees
#13 MeSH descriptor: [Immunosuppressive Agents] explode all trees
#14 MeSH descriptor: [Antibodies, Monoclonal] explode all trees
#15 MeSH descriptor: [Mycophenolic Acid] explode all trees
#16 MeSH descriptor: [Antilymphocyte Serum] explode all trees
#17 MeSH descriptor: [Tacrolimus] explode all trees
#18 MeSH descriptor: [Cyclosporine] explode all trees
#19 MeSH descriptor: [Sirolimus] explode all trees
#20 MeSH descriptor: [Muromonab‐CD3] explode all trees
#21 immunosuppres* or tacrolimus* or mycopheno* or MMF* or (monoclonal adj3 antibod*) or mab* or daclizumab* or basiliximab* or cyclosporin* or ciclosporin* or calcineurin inhibitor* or calcineurin antagonist* or purine inhibitor* or purine antagonist* or sirolimus* or rapamycin* or everolimus* or methotrexate* or azathioprine* or muromonab* or orthoclon* or OKT3* or anti‐CD3* or antithymocyte* or ATG* or anti‐IL2* or anti‐CD52* or campath* or FK506*
#22 steroid‐free* or corticosteroid‐free* or glucocorticoid‐free* or glucocorticosteroid‐free* or steroid‐sparing* or corticosteroid‐sparing* or glucocorticoid‐sparing* or glucocorticosteroid‐sparing* or steroid‐avoid* or corticosteroid‐avoid* or glucocorticoid‐avoid* or glucocorticosteroid‐avoid* or steroid‐taper* or corticosteroid‐taper* or glucocorticoid‐taper* or glucocorticosteroid‐taper* or steroid‐withdraw* or corticosteroid‐withdraw* or glucocorticoid‐withdraw* or glucocorticosteroid‐withdraw* or steroid‐eliminat* or corticosteroid‐eliminat* or glucocorticoid‐eliminat* or glucocorticosteroid‐eliminat* or steroid‐minimi* or corticosteroid‐minimi* or glucocorticoid‐minimi* or glucocorticosteroid‐minimi*
 #23 #12 OR #13 OR #14 OR #15 OR #16 OR #17 OR #18 OR #19 OR #20 OR #21 OR #22
#24 #3 AND #11 AND #23
MEDLINE Ovid 1946 to May 2017 #1 exp Liver Transplantation/
 #2 ((liver or hepat*) and (transplant* or graft*)).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier]
 #3 1 or 2
 #4 exp Steroids/
 #5 exp Glucocorticoids/
 #6 exp Adrenal Cortex Hormones/
 #7 exp Methylprednisolone/
 #8 exp Prednisone/
 #9 exp Dexamethasone/
 #10 (glucocorticosteroid* or corticosteroid* or steroid* or gluco‐corticoid* or cortico‐steroid* or methylpredniso* or methyl‐predniso* or predniso* or dexamethaso* or dexa‐methaso* or monotherapy*).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier]
 #11 4 or 5 or 6 or 7 or 8 or 9 or 10
 #12 exp Immunosuppressive Agents/
 #13 exp Antibodies, Monoclonal/
 #14 exp Tacrolimus/
 #15 exp Mycophenolic Acid/
 #16 exp Cyclosporine/
 #17 exp Sirolimus/
 #18 exp Muromonab‐CD3/
 #19 exp Antilymphocyte Serum/
 #20 (immunosuppres* or tacrolimus* or FK506* or mycopheno* or MMF* or (monoclonal adj3 antibod*) or mab* or daclizumab* or basiliximab* or cyclosporin* or ciclosporin* or calcineurin inhibitor* or calcineurin antagonist* or purine inhibitor* or purine antagonist* or sirolimus* or rapamycin* or everolimus* or methotrexate* or azathioprine* or muromonab* or orthoclon* or OKT3* or anti‐CD3* or antithymocyte* or ATG* or anti‐IL2* or anti‐CD52* or campath*).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier]
 #21 (steroid‐free* or corticosteroid‐free* or glucocorticoid‐free* or glucocorticosteroid‐free* or steroid‐sparing* or corticosteroid‐sparing* or glucocorticoid‐sparing* or glucocorticosteroid‐sparing* or steroid‐avoid* or corticosteroid‐avoid* or glucocorticoid‐avoid* or glucocorticosteroid‐avoid* or steroid‐taper* or corticosteroid‐taper* or glucocorticoid‐taper* or glucocorticosteroid‐taper* or steroid‐withdraw* or corticosteroid‐withdraw* or glucocorticoid‐withdraw* or glucocorticosteroid‐withdraw* or steroid‐eliminat* or corticosteroid‐eliminat* or glucocorticoid‐eliminat* or glucocorticosteroid‐eliminat* or steroid‐minimi* or corticosteroid‐minimi* or glucocorticoid‐minimi* or glucocorticosteroid‐minimi* or ((steroid* or corticosteroid* or glucocorticoid* or glucocorticosteroid*) adj3 (free* or spar* or avoid* or taper* or withdraw* or eliminat* or minimi* or without*))).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier]
 #22 12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21
 #23 (random* or blind* or placebo* or meta‐analys*).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept, rare disease supplementary concept, unique identifier]
 #24 3 and 11 and 22 and 23
Embase Ovid 1974 to May 2017 #1 exp Liver Transplantation/
 #2 ((liver or hepat*) and (transplant* or graft*)).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]
 #3 1 or 2
 #4 exp Steroids/
 #5 exp Glucocorticoids/
 #6 exp Adrenal Cortex Hormones/
 #7 exp Methylprednisolone/
 #8 exp Prednisone/
 #9 exp Dexamethasone/
 #10 (glucocorticosteroid* or corticosteroid* or steroid* or gluco‐corticoid* or cortico‐steroid* or methylpredniso* or methyl‐predniso* or predniso* or dexamethaso* or dexa‐methaso* or monotherapy*).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]
 #11 4 or 5 or 6 or 7 or 8 or 9 or 10
 #12 exp Immunosuppressive Agents/
 #13 exp Antibodies, Monoclonal/
 #14 exp Tacrolimus/
 #15 exp Mycophenolic Acid/
 #16 exp Cyclosporine/
 #17 exp Sirolimus/
 #18 exp Muromonab‐CD3/
 #19 exp Antilymphocyte Serum/
 #20 (immunosuppres* or tacrolimus* or FK506* or mycopheno* or MMF* or (monoclonal adj3 antibod*) or mab* or daclizumab* or basiliximab* or cyclosporin* or ciclosporin* or calcineurin inhibitor* or calcineurin antagonist* or purine inhibitor* or purine antagonist* or sirolimus* or rapamycin* or everolimus* or methotrexate* or azathioprine* or muromonab* or orthoclon* or OKT3* or anti‐CD3* or antithymocyte* or ATG* or anti‐IL2* or anti‐CD52* or campath*).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]
 #21 (steroid‐free* or corticosteroid‐free* or glucocorticoid‐free* or glucocorticosteroid‐free* or steroid‐sparing* or corticosteroid‐sparing* or glucocorticoid‐sparing* or glucocorticosteroid‐sparing* or steroid‐avoid* or corticosteroid‐avoid* or glucocorticoid‐avoid* or glucocorticosteroid‐avoid* or steroid‐taper* or corticosteroid‐taper* or glucocorticoid‐taper* or glucocorticosteroid‐taper* or steroid‐withdraw* or corticosteroid‐withdraw* or glucocorticoid‐withdraw* or glucocorticosteroid‐withdraw* or steroid‐eliminat* or corticosteroid‐eliminat* or glucocorticoid‐eliminat* or glucocorticosteroid‐eliminat* or steroid‐minimi* or corticosteroid‐minimi* or glucocorticoid‐minimi* or glucocorticosteroid‐minimi* or ((steroid* or corticosteroid* or glucocorticoid* or glucocorticosteroid*) adj3 (free* or spar* or avoid* or taper* or withdraw* or eliminat* or minimi* or without*))).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]
 #22 12 or 13 or 14 or 15 or 16 or 17 or 18 or 19 or 20 or 21
 #23 (random* or blind* or placebo* or meta‐analys*).mp. [mp=title, abstract, subject headings, heading word, drug trade name, original title, device manufacturer, drug manufacturer, device trade name, keyword]
 #24 3 and 11 and 22 and 23
Science Citation Index EXPANDED and Conference Proceedings Citation Index ‐ Science (Web of Science) 1900 to May 2017
1990 to May 2017 (Conference Proceedings)
#6 #5 AND #4
 #5 TS=(random* or blind* or placebo* or meta‐analys*)
 #4 #3 AND #2 AND #1
 #3 TS=(immunosuppres* or tacrolimus* or mycopheno* or MMF* or (monoclonal adj3 antibod*) or mab* or
 daclizumab* or basiliximab* or cyclosporin* or ciclosporin* or calcineurin inhibitor* or calcineurin antagonist* or
 purine inhibitor* or purine antagonist* or sirolimus* or rapamycin* or everolimus* or methotrexate* or azathioprine*
 or muromonab* or orthoclon* or OKT3* or anti‐CD3* or antithymocyte* or ATG* or anti‐IL2* or anti‐CD52* or
 campath*)
 #2 TS=(glucocorticosteroid* or corticosteroid* or steroid* or gluco‐corticoid* or cortico‐steroid* or methylpredniso* or
 methyl‐predniso* or predniso* or dexamethaso* or dexa‐methaso*)
 #1 TS=((liver or hepat*) and (transplant* or graft*))
Literatura Americana e do Caribe em Ciencias de Saude (LILACS) (Bireme) Bireme; 1982 to May 2017 ((liver or hepat$) and (transplant$ or graft$)) [Words] and (glucocorticosteroid$ or corticosteroid$ or steroid$ or gluco‐
 corticoid$ or cortico‐steroid$ or methylpredniso$ or methyl‐predniso$ or predniso$ or dexamethaso$ or dexa‐
 methaso$) [Words] and (immunosuppress$ or tacrolimus$ or mycopheno$ or MMF$ or monoclonal antibod$ or mab$
 or daclizumab$ or basiliximab$ or cyclosporin$ or ciclosporin$ or calcineurin inhibitor$ or calcineurin antagonist$ or
 purine inhibitor$ or purine antagonist$ or sirolimus$ or rapamycin$ or everolimus$ or methotrexate$ or azathioprine$
 or muromonab$ or orthoclon$ or OKT3$ or anti‐CD3$ or antithymocyte$ or ATG$ or anti‐IL2$ or anti‐CD52$ or
 campath$) [Words]