NCT02321163.

Trial name or title	A New Paradigm of Neuromuscular Electrical Stimulation in Attenuating Muscle Atrophy: a Randomised Controlled Trial
Methods	Randomised controlled trial
Participants	People with COPD
Interventions	NMES (2 different stimulation protocols) vs sham stimulation
Outcomes	Muscle cross‐sectional area, muscle force, muscle activation, 6MWD, protocol acceptability, discomfort during stimulation
Starting date	February 2016
Contact information	Contact: Simon S Yeung, PhD; + 852 27666705; simon.yeung@polyu.edu.hk Contact: Ella W Yeung, PhD; 852 27666748; ella.yeung@polyu.edu.hk
Notes

6MWD: six‐minute walk test; ADL: activities of daily living; BODE: Body mass index, airflow Obstruction, Dyspnea and Exercise capacity; CAT: COPD Assessment Test; CRP: C‐reactive protein; COPD: chronic obstructive pulmonary disease; HRQoL: health‐related quality of life; IL: interleukin; NMES: neuromuscular electrostimulation; TNF: tumour necrosis factor.