de la Pena‐Salcedo 2012.

Methods	Retrpospective cohort
Participants	52 patients: 40 CRRM and 12 BRRM = 64 breasts removed prophylactically from 1/1/1985 to 12/31/2010
Interventions	BRRM & CRRM, all with reconstruction
Outcomes	Physical morbidity QoL
Notes
Risk of bias
Bias	Authors' judgement	Support for judgement
Free of selection bias?	Low risk	All patients who had PM from 1/1/1985 to 12/31/2010 and did not have exclusion factors
Free of performance bias?	Low risk	The participants were included based on a review of medical records
Free of detection bias?	Low risk	The outcomes were based on a review of medical records
Free of attrition bias?	Low risk	No attrition was reported