| Study | Reason for exclusion |
|---|---|
| Abbott 2011 | About patients' estimations of risk for BC |
| Ager 2016 | About choosing CRRM |
| Alamounti 2015 | About surgical technique |
| Antill 2006 | About decision making |
| Ariyan 1985 | No original patient data presented |
| Babiera 1997 | Fewer than 20 participants |
| Barry 2012 | About incidence of CBC at time of CRRM |
| Bebbington Hatcher 2003 | No original patient data presented |
| Blackburn 2016 | About surgical technique |
| Borreani 2014 | Unable to separate data for RRM participants from other surgery participants |
| Bostwick 1980 | Surgical technique article |
| Brekelmans 2006 | About BRCA1 BC |
| Brinton 2001 | Breast reduction surgery |
| Brown 2005 | About genetic counseling |
| Buehler 1983 | About assessing risk |
| Collins 2013 | About risk‐reduction methods with no data specific to RRM |
| Cortesi 2014 | About impact of rapid genetic testing on decision making for RRM |
| Dikmans 2016 | About surgical technique |
| Dinner 1981 | Surgical technique article |
| Domchek 2011 | No data on RRM alone, intermingled with BRRSO |
| Eisinger 2001 | Physician and patient attitudes about RRM |
| Evans 2005 | About decision making |
| Fowbie 2015 | About surgical technique |
| Fu 2015 | About choosing CRRM |
| Graham 2015 | About neo‐adjuvant therapy |
| Gschwantier 2016 | About surgical technique |
| Hagen 2014 | Data combine participants with BC and without BC whether they had RRM or not |
| Han 2011 | About who chooses RRM |
| Heiniger 2015 | < 20 RRM participants |
| Hoffman 1982 | About indications for risk |
| Horton 1988 | Surgical technique article |
| Houn 1995 | Survey of physicians about RRM |
| Jarrett 1982 | Surgical technique article |
| Jones 2009 | About who chooses RRM |
| Josephson 2000 | < 20 participants |
| Katapodi 2004 | About perceived risk of BC |
| Kheirelseid 2011 | About incidence of breast cancer |
| King 2011b | About presence of occult BC in CRRM patients |
| Klitzman 2010 | About decision making |
| Kurian 2005 | About breast screening |
| Leis 1980 | About incidence of CBC |
| Lerman 1996 | Predictors of genetic testing not RRM |
| Litton 2009 | Patients' perception of their risk of BC |
| Lloyd 2000 | < 20 participants |
| Lodder 2002 | < 20 participants |
| Lynch 1991 | Original patient data presented only on predictors of compliance with surveillance |
| Lynch 2006 | About genetic testing |
| Madlensky 2005 | About prevention of BC |
| McAvoy 1979 | No original patient data presented |
| McCready 2007 | Review of risk factors for CBC |
| Meijers‐Heijboer 2003 | No data on objectives of the review |
| Metcalfe 2004c | Satisfaction with breast reconstruction following RRM |
| Metcalfe 2008a | Predictors of having CRRM in women with a BRCA1/2 mutation |
| Metcalfe 2008b | International rates of uptake of RRM in BRCA1/2 carriers |
| Metcalfe 2011a | Risk of ipsilateral BC in BRCA1/2 carriers |
| Metcalfe 2011b | Predictors of CBC in BRCA1/2 carriers |
| Meyer 1986 | No original patient data presented |
| Mulvihill 1982 | < 20 participants |
| Narod 2011 | No original patient data, used mortality tables |
| Narod 2014 | Chapter of a book |
| Nekhlyudov 2005 | About decision making |
| Osman 2013 | About surgical technique |
| Patenaude 2008 | Need for psychological support for RRM patients |
| Payne 2000 | No original patient data presented |
| Pennisi 1984 | More recent data on same cohort presented in article included in review |
| Petit 2002 | No original patient data presented |
| Phillips 2006 | Use of risk‐management strategies |
| Rhiem 2012 | Data on risk of CBC |
| Ringberg 1982 | Incidence of occult CBC |
| Roberts 2014 | About cost‐effectiveness of RRM |
| Roberts 2015 | Complications and reoperations after any mastectomy |
| Roinick 2007 | What women wished they knew about RRM |
| Rubin 1979 | Surgical technique article |
| Rueth 2011 | About pre‐operative risk‐assessment for women undergoing BRRM |
| Sakorafas 2002 | No original patient data presented |
| Salhab 2010 | Review article |
| Schwartz 2004 | About BRCA1/2 testing |
| Scott 2003 | About decision making |
| See 2005 | About decision making |
| Snyderman 1984 | About decision making |
| Spear 2008 | About reconstruction |
| Specht 2004 | About personal health behavior |
| Stalmeier 2009 | Evaluation of decision aids for high‐risk women considering RRM and/or BRRSO |
| Stefanek 1995 | < 20 participants |
| Stolier 2005 | About decision making |
| Stuckey 2010 | About who chooses BRRM |
| Temple 1991 | Surgical technique article |
| Tercyak 2007 | About impact of genetic testing and choosing CRRM |
| Theogaraj 1973 | Surgical technique |
| Tuttle 2007 | Review of SEER data on CRRM |
| Unic 1998 | About assessing risk |
| Van Dijk 2003 | About perceived risk of BC |
| von Smitten 2001 | No original patient data presented |
| Wang 2015a | Who chooses CRRM |
| Wapnir 1990 | No original patient data presented |
| Wasteson 2011 | < 20 participants |
| Yarbro 1985 | On pathophysiology of BC |
| Yi 2010 | About who chose CRRM |
| Zendejas 2011 | About cost/benefit analysis of CRRM |
BC ‐ breast cancer CBC ‐ contralateral breast cancer RRM ‐ risk‐reducing mastectomy