Rehman 2013

Methods	Randomized controlled trial Length of follow‐up: 6 days
Participants	Number: 206 enrolled children Inclusion criteria: inpatients; well‐nourished infants and children aged 6 to 24 months with watery diarrhoea < 3 days duration, with 3 watery stools per day and at least 1 in the past 24 hours; mild‐to‐severe dehydration Exclusion criteria: bloody diarrhoea, medications, malnutrition, systemic infection Breastfeeding: included
Interventions	Intervention group: diosmectite, dose 1 g in infants < 12 months and 1.5 g in older children, every 8 hours, plus zinc (dose not specified) for 5 days Control group: placebo plus zinc
Outcomes	Duration of diarrhoea (until first stool of pre‐diarrhoeal consistency)
Notes	Location: Pakistan Setting: urban Cause of diarrhoea: not specified Source of funding: not specified
Risk of bias
Bias	Authors' judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Randomized by lottery
Allocation concealment (selection bias)	Unclear risk	Insufficient information to permit judgement. Mentions only "lottery method".
Blinding of participants and personnel (performance bias) All outcomes	Low risk	Use of placebo
Blinding of outcome assessment (detection bias) All outcomes	Low risk	Use of placebo
Incomplete outcome data (attrition bias) All outcomes	Low risk	Per‐protocol analysis. 10 losses to follow‐up (5%), 4 in intervention group, 6 in control group
Selective reporting (reporting bias)	Unclear risk	Insufficient information to permit judgement. No protocol registered.
Other bias	Low risk	No other biases detected.