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. 2010 Apr 14;2010(4):CD004901. doi: 10.1002/14651858.CD004901.pub2

Comparison 3. Vaginal misoprostol versus Gemeprost (PGE1) (alone or with oxytocin).

Outcome or subgroup title No. of studies No. of participants Statistical method Effect size
1 Vaginal birth not achieved in 24 hours 3 235 Risk Ratio (M‐H, Random, 95% CI) 1.30 [0.64, 2.62]
2 Mean induction to delivery interval 2 109 Mean Difference (IV, Random, 95% CI) 2.22 [‐14.44, 18.87]
3 Pain (VAS score greater than 5) 1 100 Risk Ratio (M‐H, Fixed, 95% CI) 0.92 [0.62, 1.38]
4 Analgesia required 2 135 Risk Ratio (M‐H, Random, 95% CI) 0.80 [0.42, 1.53]
5 Mean blood loss 1 55 Mean Difference (IV, Fixed, 95% CI) ‐61.0 [‐145.71, 23.71]
6 Surgical evacuation of the uterus 3 235 Risk Ratio (M‐H, Fixed, 95% CI) 0.75 [0.55, 1.03]
7 Nausea 2 154 Risk Ratio (M‐H, Fixed, 95% CI) 1.14 [0.70, 1.86]
8 Vomiting 2 181 Risk Ratio (M‐H, Random, 95% CI) 0.85 [0.16, 4.62]
9 Diarrhoea 3 235 Risk Ratio (M‐H, Random, 95% CI) 0.48 [0.07, 3.15]
10 Pyrexia 2 154 Risk Ratio (M‐H, Random, 95% CI) 0.38 [0.13, 1.06]