Comparison 5. Vaginal misoprostol versus PGF2alpha.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Vaginal birth not achieved in 24 hours	3	213	Risk Ratio (M‐H, Random, 95% CI)	1.07 [0.28, 4.06]
1.1 Low Dose Misoprostol	2	91	Risk Ratio (M‐H, Random, 95% CI)	0.78 [0.02, 26.21]
1.2 Moderate Dose Misoprostol	0	0	Risk Ratio (M‐H, Random, 95% CI)	0.0 [0.0, 0.0]
1.3 High Dose Misoprostol	1	122	Risk Ratio (M‐H, Random, 95% CI)	0.89 [0.50, 1.58]
2 Mean induction to birth interval	4	378	Mean Difference (IV, Random, 95% CI)	‐2.84 [‐6.06, 0.38]
2.1 Low Dose Misoprostol	2	91	Mean Difference (IV, Random, 95% CI)	‐0.76 [‐11.03, 9.51]
2.2 Moderate Dose Misoprostol	0	0	Mean Difference (IV, Random, 95% CI)	0.0 [0.0, 0.0]
2.3 High Dose Misoprostol	2	287	Mean Difference (IV, Random, 95% CI)	‐3.62 [‐5.71, ‐1.53]
3 Blood loss > 500 mL	1	61	Risk Ratio (M‐H, Fixed, 95% CI)	0.69 [0.22, 2.20]
4 Need for blood transfusion	2	131	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]
5 Surgical evacuation of the uterus	5	439	Risk Ratio (M‐H, Fixed, 95% CI)	0.63 [0.41, 0.98]
6 Side effects ‐ any	1	61	Risk Ratio (M‐H, Fixed, 95% CI)	1.03 [0.41, 2.59]
7 Nausea	3	338	Risk Ratio (M‐H, Fixed, 95% CI)	0.67 [0.47, 0.95]
8 Vomiting	4	378	Risk Ratio (M‐H, Fixed, 95% CI)	0.61 [0.42, 0.89]
9 Diarrhoea	5	458	Risk Ratio (M‐H, Random, 95% CI)	0.52 [0.15, 1.82]
10 Pyrexia	5	458	Risk Ratio (M‐H, Random, 95% CI)	0.72 [0.14, 3.61]