Comparison 17. Vaginal misoprostol ‐ low (< 800 mcg cumulative dose) versus moderate (800 mcg ‐2400 mcg cumulative dose).

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Vaginal birth not achieved in 24 hours	1	150	Risk Ratio (M‐H, Fixed, 95% CI)	1.85 [1.13, 3.03]
2 Pain (VAS score > 5)	1	150	Risk Ratio (M‐H, Fixed, 95% CI)	0.89 [0.47, 1.67]
3 Need for analgesia	1	150	Risk Ratio (M‐H, Fixed, 95% CI)	0.90 [0.73, 1.10]
4 Surgical evacuation of the uterus	1	150	Risk Ratio (M‐H, Fixed, 95% CI)	0.57 [0.33, 0.98]
5 Nausea	1	150	Risk Ratio (M‐H, Fixed, 95% CI)	0.97 [0.59, 1.59]
6 Vomiting	1	150	Risk Ratio (M‐H, Fixed, 95% CI)	0.58 [0.28, 1.17]
7 Diarrhoea	1	150	Risk Ratio (M‐H, Fixed, 95% CI)	2.26 [0.80, 6.39]
8 Vaginal birth not achieved in 24 hours	0	0	Risk Ratio (M‐H, Fixed, 95% CI)	0.0 [0.0, 0.0]